The effect of epinephrine used for upper extremity anesthesia on preventing hypotension during sedation using dexmedetomidine
Not Applicable
Completed
- Conditions
- Diseases of the musculoskeletal system and connective tissue
- Registration Number
- KCT0004961
- Lead Sponsor
- Chungnam National University Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 130
Inclusion Criteria
1. age 20 ~ 65 year
2. American society of anesthesiologist physical status1~2
3. Upper extremity surgery
4. use of regional anesthesia with intraoperative sedation
Exclusion Criteria
1. other than supine position, intraoperatively
2. allergy to local anesthetics, epinephrine, dexmedetomidine
3. coagulopathy or local infection in block site
4. unable to use epinephrine or dexmedetomidine due to hemodynamic cause (uncontrolled hypertension, tachycardia, bradycardia)
5. patient refusal
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Occurrence of hypotension during and after the surgery (mBP < 60mmHg or <75% of baseline, sBP <90mmHg or <75% of baseline)
- Secondary Outcome Measures
Name Time Method Occurrence of bradycardia during and after the surgery (< 75% of baseline and <50 bpm);Maximum hemodynamic reduction during and after surgery (sBP, dBP, mBP, HR);Drug use due to hemodynamic compromise during and after surgery;length of post-anesthesia care unit stay (minutes);first request of analgesics after surgery (minutes, first dose of patient-controlled analgesia pump);cumulative dose of opioid during first 24hrs after surgery (fentanyl, mcg; PCA pump record review);other complication than hemodynamics