The effect of consuming the liposomal form of pistachio kernel oil on multiple sclerosis
Phase 3
Recruiting
- Conditions
- Multiple Sclerosis (MS).Multiple sclerosis
- Registration Number
- IRCT20201219049765N1
- Lead Sponsor
- Rafsanjan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Female
- Target Recruitment
- 500
Inclusion Criteria
Women aged 18 to 51 years
Definite diagnosis of multiple sclerosis with a descriptive measure of disability rate between 1 to 3
Exclusion Criteria
Taking corticosteroids during the study
Pregnancy and lactation
Active cardiovascular disease, liver disease, gastrointestinal disease, patients with Helicobacter pylori positive test, kidney disease, diabetes mellitus, respiratory disease and autoimmune diseases
Take multivitamin, mineral, antioxidant and pistachio kernel supplements during the 30 days before the study
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Concentration of inflammatory and anti-inflammatory factors. Timepoint: Intervention time (w0), 6 weeks after intervention (w6), 12 weeks after intervention (w12), 18 weeks after intervention (w18) and 24 weeks after intervention (w24). Method of measurement: With ELISA Kit.;Relative expression of genes of receptors of inflammatory and anti-inflammatory agents. Timepoint: Intervention time (w0), 24 weeks after intervention (w24). Method of measurement: By Realtime PCR.;The length and severity of the disease. Timepoint: Intervention time (w0), 6 weeks after intervention (w6), 12 weeks after intervention (w12), 18 weeks after intervention (w18) and 24 weeks after intervention (w24). Method of measurement: According to the descriptive measurement of disability rate.
- Secondary Outcome Measures
Name Time Method Allergies to pistachio compounds. Timepoint: Intervention time (w0), 6 weeks after intervention (w6), 12 weeks after intervention (w12), 18 weeks after intervention (w18) and 24 weeks after intervention (w24). Method of measurement: Qualitative examination with patient self-declaration.