ISRCTN98833037
Active, not recruiting
未知
Autoimmunity-informed phenotyping in chronic non-specific low-back pain
niversity of Liverpool0 sites100 target enrollmentJune 23, 2021
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- on-specific low back pain
- Sponsor
- niversity of Liverpool
- Enrollment
- 100
- Status
- Active, not recruiting
- Last Updated
- 4 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\. 18 years or older
- •2\. Presence of non\-specific LBP without the presence of another condition to explain the pain (ie. cancer, primary musculoskeletal conditions, sciatica)
- •3\. Chronic NsLBP defined as pain persisting for \>12 weeks, with pain occurring \>4 days/week
- •4\. Non\-specific LBP as defined topographically and temporally by the Delphi definition
- •5\. Average weekly pain intensity exceeding 6/10 on VAS scoring
- •6\. LBP that causes severe disability, as defined by the Modified Oswestry Low Back Pain Disability Questionnaire (MODI)
- •7\. Pain may radiate down the buttocks or backs of legs but must not radiate below the knees
- •8\. In patients with features of more widespread, non\-specific pain, the low\-back pain must be the predominant complaint of pain and the pain intensity of these other pains should not exceed 3/10 on VAS scoring
Exclusion Criteria
- •1\. Pregnant or breastfeeding patients
- •2\. Patients with immune deficiency or taking immune modulating drugs
- •3\. Patients with an acute systemic disorder
- •4\. Language other than English as first language
Outcomes
Primary Outcomes
Not specified
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