Skip to main content
Clinical Trials/ISRCTN98833037
ISRCTN98833037Active, not recruiting未知

Autoimmunity-informed phenotyping in chronic non-specific low-back pain

niversity of Liverpool0 sites100 target enrollmentStarted: June 23, 2021Last updated:
Conditions

Trial Snapshot

Phase
未知
Status
Active, not recruiting
Sponsor
Enrollment
100

Study Overview

Brief Summary

No summary available.

Study Design

Study Type
Observational

Eligibility Criteria

Sex
All

Inclusion Criteria

  • 1. 18 years or older
  • 2. Presence of non-specific LBP without the presence of another condition to explain the pain (ie. cancer, primary musculoskeletal conditions, sciatica)
  • 3. Chronic NsLBP defined as pain persisting for >12 weeks, with pain occurring >4 days/week
  • 4. Non-specific LBP as defined topographically and temporally by the Delphi definition
  • 5. Average weekly pain intensity exceeding 6/10 on VAS scoring
  • 6. LBP that causes severe disability, as defined by the Modified Oswestry Low Back Pain Disability Questionnaire (MODI)
  • 7. Pain may radiate down the buttocks or backs of legs but must not radiate below the knees
  • 8. In patients with features of more widespread, non-specific pain, the low-back pain must be the predominant complaint of pain and the pain intensity of these other pains should not exceed 3/10 on VAS scoring

Exclusion Criteria

  • 1. Pregnant or breastfeeding patients
  • 2. Patients with immune deficiency or taking immune modulating drugs
  • 3. Patients with an acute systemic disorder
  • 4. Language other than English as first language

Investigators

Sponsor
niversity of Liverpool

Similar Trials