NCT01658371已完成不适用
Preference of CYP450 2B6 516 G>T Polymorphism and Pharmacokinetics of Plasma Efavirenz in A Group of HIV Infected Southern Chinese
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- pharmacokinetics
研究概览
简要总结
Genetic polymorphism affects plasma concentration of antiretroviral therapy in HIV patients. The investigators investigate the prevalence of genetic polymorphism affecting efavirenz metabolism and the corresponding pharmacokinetics of different genotypes.
详细描述
Eligible patients are invited to donate blood samples for pharmacokinetic study and genotype analysis
研究设计
- 研究类型
- Observational
- 时间视角
- Cross Sectional
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Southern Chinese HIV patients on efavirenz
排除标准
- •Refuse to sign consent, HIV patients not on efavirenz
结局指标
主要结局
pharmacokinetics
时间窗: 24 hour
This includes plasma concentration of drugs in relation to time, in different genotypes
次要结局
- genotypes frequency(1 year)
研究者
To Kin Wang
Specialist
Chinese University of Hong Kong
研究点 (1)
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