Microbiome in Atopic Dermatitis Under Systemic Therapy
Recruiting
- Conditions
- Atopic Dermatitis
- Registration Number
- NCT05099315
- Lead Sponsor
- Charite University, Berlin, Germany
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 600
Inclusion Criteria
Inclusion Criteria:<br><br> - Patients with moderate to severe atopic dermatitis<br><br> - Indication for systemic therapy<br><br>Exclusion Criteria:<br><br> - Patients under 18 years of age upon introducing systemic therapy<br><br> - Pregnant and lactating women
Exclusion Criteria
Not provided
Study & Design
- Study Type
- Observational [Patient Registry]
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Comparison of the microbial composition;Comparison of microbial composition of the skin with serological biomarkers
- Secondary Outcome Measures
Name Time Method Microbial composition and skin barrier function;Correlation of main microbial representants of skin microbiome;Correlation of microbiome and severity of atopic dermatitis EASI;Correlation of microbiome and severity of atopic dermatitis SCORAD;Association of the skin microbiome with the mRNA EASI;Association of the skin microbiome with the mRNA SCORAD