跳至主要内容
临床试验/NCT06734338
NCT06734338
招募中
不适用

Validation of the STUMBL Score for Risk Stratification in Emergency Department Patients With Blunt Thoracic Trauma: A Prospective Observational Study in Iraq

Al-Nahrain University1 个研究点 分布在 1 个国家目标入组 188 人2025年4月20日
适应症Chest Trauma

概览

阶段
不适用
干预措施
未指定
疾病 / 适应症
Chest Trauma
发起方
Al-Nahrain University
入组人数
188
试验地点
1
主要终点
In hospital mortality
状态
招募中
最后更新
上个月

概览

简要总结

This prospective observational study aims to validate the STUMBL score for risk stratification in emergency department patients with blunt thoracic trauma in Iraq. The main questions it seeks to answer are:

How accurately does the STUMBL score predict mortality and critical outcomes such as ICU admission or advanced interventions? How well does the score stratify patients by injury severity in a resource-limited setting? Are there demographic or clinical factors that influence the score's predictive performance?

Participants will:

Be assessed using the STUMBL score upon arrival at the emergency department to predict risk levels.

Have demographic and clinical data, including age, gender, injury mechanism, comorbidities, and length of hospital stay, collected to explore potential associations with outcomes.

详细描述

Blunt thoracic trauma (BTT) is a significant cause of morbidity and mortality in emergency department (ED) patients worldwide. The complexity of BTT management arises from the diverse range of injuries that can occur, including rib fractures, pneumothorax, and hemothorax, which can lead to life-threatening complications if not promptly identified and treated. Studies indicate that the rise in mortality and long-term morbidity can be clearly linked to the number of rib fractures sustained. Road traffic collisions are the predominant cause of major blunt injury. BTT is more common, with relative incidence being estimated at 72-83.5% versus penetrating trauma at 16.5-28%. In emergency settings, timely and accurate assessment of patients with blunt thoracic injuries is crucial for optimizing outcomes. Thereby, there is a need for valid systems that can be effectively utilized in emergency departments to enhance clinical decision-making in a short-term manner. The STUMBL (STUdy of the Management of BLunt chest wall trauma) score was developed to assist in clinical decision-making for patients with blunt chest wall trauma. This model includes five risk factors: patient age, the number of rib fractures, chronic lung disease, pre-injury use of anticoagulants, and oxygen saturation levels. Unlike other scoring systems that focus solely on anatomical variables and age, the STUMBL score uniquely incorporates clinical variables such as chronic lung disease and anticoagulation. A huge benefit of the STUMBL score is that these variables are all routinely measured in the ED. The score has reached a sensitivity of 80%, a specificity of 96%, a positive predictive value (PPV) of 93%, and a negative predictive value (NPV) of 86% for predicting complications following blunt chest wall trauma. By integrating essential clinical parameters, the STUMBL score helps clinicians identify patients at high risk for adverse outcomes. Each patient is evaluated based on several risk factors. A final risk score of ≥11 indicates a significant risk of developing complications, and a total risk score exceeding 25 is considered sufficiently high to require admission to the intensive care unit (ICU). The STUMBL score has shown potential across various healthcare settings. However, its validation in varied populations, especially in low-resource areas, remains limited. In the context of Iraqi EDs, the applicability of the STUMBL score has not been thoroughly investigated. As healthcare systems face challenges related to resource, training, and infrastructure limitations, the integration of evidence-based tools like the STUMBL score could significantly improve patient care. The burden of trauma is compounded by ongoing conflict and limited healthcare resources, leading to an urgent need for effective trauma management protocols. This study aims to evaluate the performance of the STUMBL score among ED patients presenting with blunt thoracic trauma in Iraq.

注册库
clinicaltrials.gov
开始日期
2025年4月20日
结束日期
2026年12月20日
最后更新
上个月
研究类型
Observational
性别
All

研究者

发起方
Al-Nahrain University
责任方
Principal Investigator
主要研究者

Abdulillah R. Khamees

Principal Investigator

Al-Nahrain University

入排标准

入选标准

  • Patients presenting to the emergency department with blunt thoracic trauma (e.g., motor vehicle accidents, falls, or direct impacts to the chest).
  • Patients who present within 4 hours of sustaining the injury.
  • Patients or their legal guardians must provide informed consent to participate in the study.

排除标准

  • Patients with penetrating chest trauma (e.g., stab wounds, gunshot wounds).
  • Patients with other life-threatening injuries that overshadow the thoracic trauma (e.g., head or abdominal trauma).
  • Pregnant women due to potential risks related to radiation or certain diagnostic procedures.
  • Pediatric patients under 18 years of age.
  • Patients with a history of major thoracic surgery (e.g., prior lung or heart surgery) that may interfere with the assessment of trauma severity.

结局指标

主要结局

In hospital mortality

时间窗: In-Hospital Phase (average of 10 days through discharge); Post-Discharge Follow-Up: Day 7, Day 30

Mortality (death) during hospitalization.

Accuracy Assessment of the STUMBL score

时间窗: the first 4 hours after ER admission

The score ranges from 1 to 30. ≥11 is particularly significant, as it indicates a higher risk of complications.

次要结局

  • Length of Hospitalization(Up to discharge, an average of 10 days)
  • Rate of ICU Admission(Up to discharge, an average of 10 days)
  • Rate of Participants Requiring Surgical Intervention(Up to discharge, an average of 10 days)

研究点 (1)

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