Early Left Atrial Septostomy Versus Conventional Approach after Venoarterial Extracorporeal Membrane Oxygenation: A Randomized Controlled Study

Chonnam National University Hospital0 个研究点目标入组 116 人开始时间: 待定最近更新: 2024年3月4日

试验速览

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•1) Age more than 18 years old
•2) Cardiogenic shock*
•3) Successful VA-ECMO implantation
•* The definition of cardiogenic shock
•All these criteria should be met
•1) Systolic blood pressure < 90 mmHg for 30 minutes, or needing inotropics or vasopressor to maintain systolic blood pressure > or = 90 mmHg
•2) Pulmonary congestion on chest X-ray or increased left ventricular filling pressure by cardiac catheterization
•3) At least one criteria of organ dysfunction
•- mental obtundation, clammy ski, ogliuria, renal dysfunction, increased level of blood lactate

•1) VA-ECMO after open heart surgery
•2) VA-ECMO for the treatment of non-cardiac shock
•3) Severe bleeding*
•4) Terminal malignancy
•5) Irreversible brain damage
•6) Pregnancy or lactation
•* The definition of severe bleeding
•Hemoglobin decrease after VA-ECMO or cannulation site bleeding is not a exclusion criteria
•1) Hypovolemic shock due to definite bleeding cause
•2) Identifiable bleeding causes: gastrointestinal bleeding, hemothorax, traumatic bleeding, CNS hemorrhage, pulmonary hemorrhage

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