Skip to main content
Clinical Trials/NCT06121037
NCT06121037
Completed
Not Applicable

Greater Occipital Nerve Pulsed Radiofrequency for the Treatment of Combined Migraine and Cervicogenic Headache (New Approach): Randomized Clinical Trial

Assiut University1 site in 1 country60 target enrollmentJanuary 1, 2022

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Greater Occipital Nerve
Sponsor
Assiut University
Enrollment
60
Locations
1
Primary Endpoint
Numerical rating score
Status
Completed
Last Updated
2 years ago

Overview

Brief Summary

Combined migraine and cervicogenic headache present significant challenges in clinical management due to their complex and overlapping pathophysiologies. Both conditions involve the trigeminocervical complex, suggesting a potential shared anatomical and neurobiological basis

Detailed Description

Traditional treatment approaches for these headaches often include pharmacological interventions, but in cases of refractory or inadequate response, interventional techniques targeting the greater occipital nerve (GON) have gained attention. Radiofrequency ablation (RFA) has gained recognition as a potential therapeutic option for patients with refractory combined migraine and cervicogenic headaches. The proximal and distal ultrasound-guided approaches are widely utilized for GON RFA. These approaches aim to disrupt pain signals transmitted by the GON and provide relief of pain for these headache disorders

Registry
clinicaltrials.gov
Start Date
January 1, 2022
End Date
September 1, 2023
Last Updated
2 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Ghada Mohammed AboelFadl

Principal investigator

Assiut University

Eligibility Criteria

Inclusion Criteria

  • Patients diagnosed with combined migraine and cervicogenic headache according to The International Classification of Headache Disorders (ICHD)
  • Age between 18 and 65 years.
  • Willingness to participate and provide informed consent

Exclusion Criteria

  • Previous neurosurgical procedures for headache management.
  • Patients with contraindications for the RF technique
  • Pregnancy or lactation
  • History of psychiatric disorders or substance abuse

Outcomes

Primary Outcomes

Numerical rating score

Time Frame: baseline and at follow-up visits (2 weeks.1, 2.3, and 6 months)

0-10 scale, with 0 indicating no pain and 10 indicating the worst possible pain.

Study Sites (1)

Loading locations...

Similar Trials