Greater Occipital Nerve Pulsed Radiofrequency for the Treatment of Combined Migraine and Cervicogenic Headache (New Approach)

Not Applicable

Completed

• Conditions: Greater Occipital Nerve; Pulsed Radiofrequency
• Interventions: Procedure: proximal ultrasound-guided GON radiofrequency ablation; Procedure: distal ultrasound-guided GON radiofrequency ablation

• Registration Number: NCT06121037
• Lead Sponsor: Assiut University

Brief Summary

Combined migraine and cervicogenic headache present significant challenges in clinical management due to their complex and overlapping pathophysiologies. Both conditions involve the trigeminocervical complex, suggesting a potential shared anatomical and neurobiological basis

Detailed Description

Traditional treatment approaches for these headaches often include pharmacological interventions, but in cases of refractory or inadequate response, interventional techniques targeting the greater occipital nerve (GON) have gained attention.

Radiofrequency ablation (RFA) has gained recognition as a potential therapeutic option for patients with refractory combined migraine and cervicogenic headaches. The proximal and distal ultrasound-guided approaches are widely utilized for GON RFA. These approaches aim to disrupt pain signals transmitted by the GON and provide relief of pain for these headache disorders

Study Timeline

• Study Start: 2022-01-01
• Primary Completion: 2023-08-01
• Study Completion: 2023-09-01
• Status Verified: 2023-11
• Study First Submitted: 2023-11-02
• Study First Submitted QC: 2023-11-02
• Last Update Submitted: 2023-11-06
• Study First Posted: 2023-11-07
• Last Update Posted: 2023-11-08

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• Patients diagnosed with combined migraine and cervicogenic headache according to The International Classification of Headache Disorders (ICHD)
• Age between 18 and 65 years.
• Willingness to participate and provide informed consent

Exclusion Criteria

• Previous neurosurgical procedures for headache management.
• Patients with contraindications for the RF technique
• Pregnancy or lactation
• History of psychiatric disorders or substance abuse

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Proximal group	proximal ultrasound-guided GON radiofrequency ablation	proximal ultrasound-guided GON radiofrequency ablation
Distal group	distal ultrasound-guided GON radiofrequency ablation	distal ultrasound-guided GON radiofrequency ablation

Primary Outcome Measures

Name	Time	Method
Numerical rating score	baseline and at follow-up visits (2 weeks.1, 2.3, and 6 months)	0-10 scale, with 0 indicating no pain and 10 indicating the worst possible pain.

Trial Locations

Locations (1)

Assiut governorate; 🇪🇬 Assiut, Egypt