Greater Occipital Nerve Pulsed Radiofrequency for the Treatment of Combined Migraine and Cervicogenic Headache (New Approach): Randomized Clinical Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 60
- 试验地点
- 2
- 主要终点
- Numerical rating score
研究概览
简要总结
Combined migraine and cervicogenic headache present significant challenges in clinical management due to their complex and overlapping pathophysiologies. Both conditions involve the trigeminocervical complex, suggesting a potential shared anatomical and neurobiological basis
详细描述
Traditional treatment approaches for these headaches often include pharmacological interventions, but in cases of refractory or inadequate response, interventional techniques targeting the greater occipital nerve (GON) have gained attention.
Radiofrequency ablation (RFA) has gained recognition as a potential therapeutic option for patients with refractory combined migraine and cervicogenic headaches. The proximal and distal ultrasound-guided approaches are widely utilized for GON RFA. These approaches aim to disrupt pain signals transmitted by the GON and provide relief of pain for these headache disorders
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients diagnosed with combined migraine and cervicogenic headache according to The International Classification of Headache Disorders (ICHD)
- •Age between 18 and 65 years.
- •Willingness to participate and provide informed consent
排除标准
- •Previous neurosurgical procedures for headache management.
- •Patients with contraindications for the RF technique
- •Pregnancy or lactation
- •History of psychiatric disorders or substance abuse
结局指标
主要结局
Numerical rating score
时间窗: baseline and at follow-up visits (2 weeks.1, 2.3, and 6 months)
0-10 scale, with 0 indicating no pain and 10 indicating the worst possible pain.
次要结局
未报告次要终点
研究者
Ghada Mohammed AboelFadl
Principal investigator
Assiut University