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临床试验/NCT02332382
NCT02332382Unknown不适用

The Influence of Mother Nutrition on the Composition of Fatty Acid, Oligosacharides and Its Effect on Breast Milk Microbiome

Sheba Medical Center0 个研究点目标入组 20 人开始时间: 2015年2月最近更新:
适应症

试验速览

阶段
不适用
入组人数
20
主要终点
Change in breast milk composition in relation to nutritional intake

研究概览

简要总结

The research subject

Health organizations around the world have determined that breastfeeding is the most critical source of nutrition for newborns in the first weeks and months of their lives. A mother's breast milk contains unique nutritious components and other nonnutritive elements that help promote healthy baby growth and development (1, 2). Recent studies show that a mother's breast milk contains components that vary from each specimen. There are great evidences that maternal and environmental factors have a strong influence on the composition of breast milk. Fatty acids, the second most common component found in breast milk, show extreme sensitivity to maternal nutrition (3, 4).

Latest studies show that breast milk also contains bacterial communities that may have health implications of newborn. The structure of these bacterial communities also varied greatly between subjects (5) .

In the research, we propose to investigate the connection between maternal nutrition, different fatty acids and their role in the growth and development of bacterial populations existing in breast milk.

研究设计

研究类型
Observational
观察模型
Case Only
时间视角
Prospective

入排标准

性别
Female
接受健康志愿者

入选标准

  • Healthy lactating women, breast feeding for the first 3 months after delivery

排除标准

  • No compliance, sickness, drug consumption

结局指标

主要结局

Change in breast milk composition in relation to nutritional intake

时间窗: 3 months

次要结局

未报告次要终点

研究者

申办方类型
Other Gov
责任方
Principal Investigator
主要研究者

Prof. Yoram Bujanover MD

Head pediatric gastroenterology service

Sheba Medical Center

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