The Influence of Mother Nutrition on the Composition of Fatty Acid, Oligosacharides and Its Effect on Breast Milk Microbiome
试验速览
- 阶段
- 不适用
- 入组人数
- 20
- 主要终点
- Change in breast milk composition in relation to nutritional intake
研究概览
简要总结
The research subject
Health organizations around the world have determined that breastfeeding is the most critical source of nutrition for newborns in the first weeks and months of their lives. A mother's breast milk contains unique nutritious components and other nonnutritive elements that help promote healthy baby growth and development (1, 2). Recent studies show that a mother's breast milk contains components that vary from each specimen. There are great evidences that maternal and environmental factors have a strong influence on the composition of breast milk. Fatty acids, the second most common component found in breast milk, show extreme sensitivity to maternal nutrition (3, 4).
Latest studies show that breast milk also contains bacterial communities that may have health implications of newborn. The structure of these bacterial communities also varied greatly between subjects (5) .
In the research, we propose to investigate the connection between maternal nutrition, different fatty acids and their role in the growth and development of bacterial populations existing in breast milk.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Healthy lactating women, breast feeding for the first 3 months after delivery
排除标准
- •No compliance, sickness, drug consumption
结局指标
主要结局
Change in breast milk composition in relation to nutritional intake
时间窗: 3 months
次要结局
未报告次要终点
研究者
Prof. Yoram Bujanover MD
Head pediatric gastroenterology service
Sheba Medical Center
