Effectiveness of T-PRF and DFDBA in socket preservation for implant placement.

Not yet recruiting

Conditions: Root piece

Registration Number: CTRI/2021/12/038608

Lead Sponsor: Sharad Pawar Dental College and Hospital

Brief Summary: **ABSTRACT**

**Background:** Implant dentistry has evolved over time with variousnovel protocols. The focus of the implant therapy is nowshifting to a stable restoration rather than mere osseointegration. Placement of dental implants has become anindispensable part of mainstream dentistry, offering an improved quality oflife to patients. The primary indicator for the repair or preservation ofosseous structures following disease or trauma is the rehabilitation ofedentulous ridges to allow the installation of endosseous implants. One of thephysiological changes that occurs after tooth extraction is alveolar ridgeresorption. The first yearafter tooth extraction sees major dimensional shifts in the extraction socket,with two-thirds of the bone loss occurring during the first three months. A variety of bone graft materials and platelet concentrates whichare abundant in growth factors have been incorporated that provides the addedeffect of combination for early and better healing.

**Objectives:** Evaluation of effectiveness of â€œTitanium Prepared Platelet RichFibrinâ€(T-PRF) and â€œDemineralized Freeze-Dried Bone Graftâ€(DFDBA) in socketpreservation and simultaneous evaluation of implant stability three months after implant placement using twostage protocol.

**Methodology:** Present study will be performed over one year period. Twelvepatients, each having one tooth indicated for extraction in either of thearches will be selected. Atraumatic extraction will be done followed by socketpreservation using combination of T-PRF and DFDBA to promote early healingfollowed by placement of implant.

**Expected results:** We expect early and better results of bone formation in healingsockets after preservation using T-PRF and DFDBA, which will be advantageousfor implant placement. Better results in terms of bone volume, bone height,bone density and histomorphometry are expected.

**Conclusion: C**ombination of T-PRF and DFDBA is expected ofcreating novel outcomes.

**Keywords:** T-PRF, Socket Preservation, Dental Implant, DFDBA.

Detailed Description: Not available

Recruitment & Eligibility

Status: Not Yet Recruiting

Sex: All

Target Recruitment: 12

Inclusion Criteria

Inclusion criterias: 1.Tooth indicated for extraction.
Reasons might be any one like, fracture of root, failure of endodontic treatment, resorption (internal and external), over-retained primary teeth, non-restorable carious lesions, residual roots.
2.Oral hygiene indicated with plaque score â‰¤ 25%.
3.Presence of opposing natural tooth.
4.Presence of adjacent teeth.
5.Thick gingival biotype.
6.Radiographic and clinical appearance of intact alveolar bony walls.
4 mm of bone radiographically at root apex 8.D-1, D-2 or D-3 bone quality.

Exclusion Criteria

Exclusion criterias: 1.Patients with impaired systemic health that would interfere with the process involved with repair and healing of bones e.g. (Diabetes mellitus, Osteoporosis, Blood disorders, and Titanium allergy).
2.Significant differences in maxilla-mandibular space.
3.Presence of para functional habits such as bruxism or clenching.
4.Presence of proclined teeth, teeth with interdental spacing, rotated or mal-aligned anterior teeth.
5.History of alcoholism, excessive smoking or drug abuse.
6.D-4 bone quality.
7.Width of keratinized gingiva less than 2mm at implant site.
8.Debilitating tempro-mandibular joint pathosis.
9.Untreated dental diseases.
10.Pregnant and lactating mothers.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
3. To evaluate success rate of delayed implant placement in ridge preservation / socket preservation.	To be evaluated after 3 months of ridge preservation and then after 3 months of implant placement
2. To evaluate vertical and horizontal crestal bone changes around post extraction implant placement.	To be evaluated after 3 months of ridge preservation and then after 3 months of implant placement
1. To evaluate bucco-lingual changes of sockets before and after ridge preservation.	To be evaluated after 3 months of ridge preservation and then after 3 months of implant placement

Secondary Outcome Measures

Name	Time	Method

Trial Locations

Locations (1): Sharad Pawar Dental College and Hospital
🇮🇳
Wardha, MAHARASHTRA, India
Sharad Pawar Dental College and Hospital
🇮🇳Wardha, MAHARASHTRA, India
Dr Ranu Oza
Principal investigator
07588415693
ranuoza@gmail.com