The benefits of early inotropic administration compared to refractory phase inotropic administration in pediatric patients with septic shock

Phase 3

Completed

• Conditions: Improvement in the outcome of pediatric patients with septic shock by early administration of inotropic; Infections and Infestations

• Registration Number: ISRCTN40192699
• Lead Sponsor: dayana University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2021-04-30
• Study Start: 2023-01-26
• Last Update Posted: 6 February 2023

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 13

Inclusion Criteria

1. Pediatric patients diagnosed with septic shock and presenting to the pediatric emergency department of RS Prof Ngoerah between December 2019 and December 2020
2. Pediatric patients whose parents agree to sign the informed consent

Exclusion Criteria

1. Pediatric patients with congenital diseases, such as congenital heart disease
2. Undergoing therapy for renal diseases
3. History of prematurity
4. Fluid resuscitation has been done in other healthcare facilities

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Ferritin levels in blood samples measured using a ferritin test at 1, 6, and 24 hours following the administration of epinephrine

Secondary Outcome Measures

Name	Time	Method
<br> Levels in blood samples at 1, 6, and 24 hours following administration of epinephrine:<br> 1. Leukocytes measured using a white blood cell count<br> 2. C-Reactive Protein (CRP) measured using a CRP test<br> 3. Troponin-I measured using a troponin test<br> 4. Lactate measured using a lactic acid test<br> 5. Oxygen saturation measured using a pulse oximeter<br>