Effect of Dissolving Xylitol Chewable Tablets Versus Xylitol Chewing Gum on Salivary pH and Bacterial Count in Geriatric Bedridden Patients : Randomized Clinical Trial
试验速览
- 阶段
- 早期 1 期
- 入组人数
- 98
- 试验地点
- 1
- 主要终点
- Salivary bacterial count
研究概览
简要总结
This study will be conducted to evaluate the effectiveness of using dissolving Xylitol chewable tablets versus xylitol chewing gum with bedridden geriatric patients in increasing salivary pH and decreasing bacterial count in both saliva and interdental plaque.
详细描述
This study will be conducted to evaluate the value of using dissolving Xylitol chewable tablets versus xylitol chewing gum with bedridden geriatric patients ,as an alternative to tooth brushing and mouth rinsing, in increasing salivary pH and decreasing bacterial count in both saliva and interdental plaque.plaque and salivary sampling will be taken in certain time ,at baseline T0, then after 5minutes T1, then at 15 days T3. Salivary pH will be measured by using pH meter and streptococcus mutans bacterial count will be calculated through culture in mitis salivarius bacitracin
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Double (Investigator, Outcomes Assessor)
盲法说明
The operator will be blinded to material and assessors will be blinded to the material assignment.
入排标准
- 年龄范围
- 65 Years 至 —（Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Age range above 65 years old
- •Bedridden patients
- •Males or females
- •Concious patients
- •Co-operative patients approving to participate in the trial.
- •Subjects who signed informed consent
排除标准
- •Individuals had taken antibiotics during the last four weeks or anticipated doing so during the study
- •Subjects who wore removable prosthesis
- •Patients with systemic diseases that have any oral manifestations
- •History of Smoking
- •Allergy to any of chewing gum or tablets ingredients
- •Evidence of tempromandibular joint disorders
- •Presence of intraoral infections
- •Currently using any mouth rinse
研究组 & 干预措施
Dissolving xylitol chewable tablets
Listerine ready tabs 3 times/day
干预措施: Listerine ready tabs (Drug)
Xylitol chewing gum
Trident original 3 times/day
干预措施: Listerine ready tabs (Drug)
结局指标
主要结局
Salivary bacterial count
时间窗: 15 days
Streptococcus mutans count in saliva
次要结局
- Interdental plaque Bacterial count(15 days)
研究者
Manar abd elmageed ahmed
Manar abd El mageed ahmed
Cairo University