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临床试验/NCT05628935
NCT05628935已完成不适用

The Effect of Anesthesia Method on Neutrophil-Lymphocyte Ratio in Patients Undergoing Forearm Surgery

Zonguldak Bulent Ecevit University1 个研究点 分布在 1 个国家目标入组 1 人开始时间: 2018年1月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
1
试验地点
1
主要终点
Neutrophil/lymphocyte ratio

研究概览

简要总结

The neutrophil/lymphocyte ratio (NLR) is a simple and inexpensive marker of the inflammatory response. NLR is affected not only by surgical trauma but also by the anesthetic method. The method of anesthesia can affect NLR, thereby modulating the inflammatory response and surgical outcomes. In this study, it was aimed to evaluate the relationship between blood NLR and anesthesia techniques in patients undergoing forearm surgery, and the secondary aim was to evaluate the relationship between Platelet/lymphocyte ratio (TLR), Mean Platelet Volume (MPV) and anesthesia techniques.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 70 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Underwent forearm surgery
  • Between aged 18-70
  • Under general anesthesia or peripheral nerve block

排除标准

  • acute infection
  • morbid obesity
  • chronic treatment with steroids or immunosuppressants
  • recently received chemotherapy
  • hepatic and renal dysfunction;
  • chronic alcohol abusers
  • Multiple trauma
  • Patients with missing data in their files

结局指标

主要结局

Neutrophil/lymphocyte ratio

时间窗: up to 24 hours after surgery

Differences in neutrophil-lymphocyte ratio between patients who underwent general anesthesia and peripheral nerve block

次要结局

  • Platelet/lymphocyte ratio(up to 24 hours after surgery)
  • Mean Platelet Volume(up to 24 hours after surgery)

研究者

发起方
Zonguldak Bulent Ecevit University
申办方类型
Other
责任方
Principal Investigator
主要研究者

Bengü Gülhan Köksal

medical doctor

Zonguldak Bulent Ecevit University

研究点 (1)

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