Supine Versus Left Lateral Tilted Position During Cesarean Delivery
- Conditions
- Cesarean Section Complications
- Interventions
- Registration Number
- NCT03182114
- Lead Sponsor
- Cairo University
- Brief Summary
In this study, we will investigate the effect of left lateral tiling performed after spinal block on maternal hemodynamics compared to ordinary supine position
- Detailed Description
Maternal hypotension is a common complication after spinal anesthesia for cesarean delivery (CD). Aortocaval compression is one of the theoretical mechanisms precipitating for post-spinal hypotension (PSH) for CD. Positioning of the patients in the left lateral tilted position after preforming spinal block was frequently considered a standard protocol for minimizing aortocaval compression and improve maternal hemodynamics during CD; however, the latest Cochrane database review reported that there is no adequate evidence to support any positioning protocol for prevention of PSH. Moreover, a recent study was conducted in full term pregnant women reporting no improvement in cardiac output with left lateral tilting. In this study, the effect of left lateral tiling performed after spinal block on maternal hemodynamics will be compared to ordinary supine position.
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- Female
- Target Recruitment
- 450
- full term
- singleton pregnant women
- scheduled for elective cesarean delivery
- Cardiac morbidities
- hypertensive disorders of pregnancy
- peripartum bleeding
- baseline systolic blood pressure (SBP) < 100 mmHg
- body mass index > 35
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description supine position supine position the patient will receive spinal anesthesia by Bupivacaine; then she will be placed in supine position Left lateral tilted position left lateral tilted position the patient will receive spinal anesthesia by Bupivacaine; then she will be placed in left lateral tilted position supine position Bupivacaine the patient will receive spinal anesthesia by Bupivacaine; then she will be placed in supine position Left lateral tilted position Bupivacaine the patient will receive spinal anesthesia by Bupivacaine; then she will be placed in left lateral tilted position
- Primary Outcome Measures
Name Time Method postspinal hypotension 30 minutes after spinal anesthesia The number of patients who develop hypotension (defined as decreased SBP less than 80% of the baseline reading during the period from intrathecal injection till delivery of the fetus) after spinal block divided by the total number in the group
- Secondary Outcome Measures
Name Time Method severe postspinal hypotension 30 minutes after spinal anesthesia The number of patients who develop hypotension (defined as decreased SBP less than 60% of the baseline reading during the period from intrathecal injection till delivery of the fetus) after spinal block divided by the total number in the group
Post-delivery hypotension 10 minutes after delivery number of patients who develop hypotension (defined as decreased SBP less than 80% of the baseline reading after delivery of the fetus and starting oxytocin infusion
systolic blood pressure 60 minutes after spinal block systolic blood pressure measured in mmHg
diastolic blood pressure 60 minutes after spinal block diastolic blood pressure measured in mmHg
incidence of nausea and vomiting 60 minutes after spinal block number of patients who develop nausea and vomiting divided by the total number of patients in the group
ephedrine consumption 60 minutes after spinal block total amount of ephedrine consumed during the operation (measured in milligrams)
Atropine consumption 60 minutes after spinal block total amount of atropine consumed during the operation (measured in milligrams
heart rate 60 minutes after spinal block heart rate measured in beats per minute
APGAR score 10 minute after delivery APGAR score for detection of the well being of the fetus
Trial Locations
- Locations (1)
Cairo University
🇪🇬Cairo, Egypt