Survey to assess mucosal and humeral polio-immunity in Gadap, Karachi, Pakista

• Conditions: Polio; immunity to poliovirus; Infection - Other infectious diseases

• Registration Number: ACTRN12619000357156
• Lead Sponsor: World Health Organization

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2019-03-06
• Last Update Posted: 15 July 2019

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 600

Inclusion Criteria

children living in study catchment area (Gadap Union Council 04, Karachi, Pakistan) aged 1-2 years or 4-5 years or 9-10 years or 14-15 years

Exclusion Criteria

Suspected immunodeficiecny

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Excretion of polio vaccine poliovirus (Sabin virus) measured by isolation of type specific poliovirus in stool[one week after receipt of bOPV ]

Secondary Outcome Measures

Name	Time	Method
Difference in excretion of polio vaccine poliovirus (Sabin virus) measured by isolation of type specific poliovirus in stool (serotype 1) between the intervention and comparator study arms[one week after administration of bOPV];Difference in excretion of polio vaccine poliovirus (Sabin virus) measured by isolation of type specific poliovirus in stool (serotype 3) between the intervention and comparator study arms[one week after administration of bOPV]