Comparison of different doses of ketamine and propofol for changing the dressing in burn patients

Phase 3

Recruiting

• Conditions: Second- and third-degree burns.; Encounter for change or removal of nonsurgical wound dressing; Z48.00

• Registration Number: IRCT20201210049672N2
• Lead Sponsor: Vice-Chancellery for Research Hormozgan University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 4 April 2022

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 120

Inclusion Criteria

Age 15-65 years
Second- and third-degree burns
Burn area of 10-70%
Daily dressing change before skin graft in the operating room with American Society of Anesthesiologists (ASA) class 1-3
Ability to speak and perceive the Persian language

Exclusion Criteria

Drug addiction
Respiratory and cardiac diseases
Renal disorders
Hypersensitivity to analgesic drugs, ketamine, and propofol
History of psychiatric disorders
History of seizure
American Society of Anesthesiologists (ASA) class >3

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Pain intensity. Timepoint: At the end of the procedure. Method of measurement: Visual Analogue Scale.

Secondary Outcome Measures

Name	Time	Method
Sedation. Timepoint: At the end of the procedure. Method of measurement: Ramsay Sedation Scale.;Patient satisfaction. Timepoint: At the end of the procedure. Method of measurement: Poor/moderate/good/excellent.;Surgeon satisfaction. Timepoint: At the end of the procedure. Method of measurement: Poor/moderate/good/excellent.