A comparison of effects of intravenous dexmedetomidine and paracetamol in bupivacaine spinal anesthesia in lower abdominal and pelvic surgeries.

Department of Anaesthesia and Intensive Care0 个研究点目标入组 0 人开始时间: 待定最近更新: 2021年11月24日

试验速览

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•1. American Society of Anesthesiologists (ASA) class I or II
•2. Age: 18 to 70 years
•3. Measuring 150-180 cm height, with body mass index (BMI) of 18-35 kg/m2
•4. Patients undergoing elective lower abdominal and pelvic surgeries requiring spinal anaesthesia (maximum surgery duration-2hours)

•1. All contraindications to spinal analgesia including bleeding diathesis, infection at the puncture site, spinal deformity, patient on anticoagulants, pre-existing neurological deficits in lower extremities, unwillingness to give consent.
•2. Sensory blockade inadequate for surgery.
•3. Patients on alpha-2 adrenergic receptors antagonists, calcium channel blockers, or angiotensin-converting enzyme inhibitors.
•4. Patients having cardiac rhythm abnormalities.
•5. History of alcoholism, drug abuse, and psychiatric disorders.
•6. History of allergy to any of the study drugs.
•7. Hepatic disease, renal disease, cardiopulmonary disease, hypertension,
•diabetes, central or peripheral nervous system disorders.
•8. Laparotomy, chronic abdominal pain undergoing treatment with opioid analgesic.
•9. Pregnant patients.
•10. Orthopaedic surgeries.
•11. Surgeries extending more than 2 hours.

发起方

Department of Anaesthesia and Intensive Care