Comparison of the Efficacy of Ultrasound-Guided Corticosteroid Injection and Paraffin Therapy in Carpal Tunnel Syndrome
- Conditions
- Carpal Tunnel Syndrome
- Registration Number
- NCT06658886
- Lead Sponsor
- Beylikduzu State Hospital
- Brief Summary
The aim of this study is to compare the efficacy of paraffin therapy, a physical therapy modality, and ultrasound-guided corticosteroid injection in the treatment of carpal tunnel syndrome, the most common entrapment neuropathy. By doing so, the study will evaluate the effectiveness and feasibility of these two alternative, low-side-effect treatments for managing this frequently encountered condition.
- Detailed Description
A total of 46 patients, aged 18-65, diagnosed with mild to moderate carpal tunnel syndrome based on electrophysiological studies, will be included in the study.Pain levels will be assessed using the Visual Analog Scale (VAS), and functional impairment will be measured with the Boston Carpal Tunnel Syndrome Questionnaire (BCTQ). Electrophysiological evaluations will be performed by a neurology specialist at the 1st and 3rd month follow-ups outside of working hours and without being billed to the Social Security Institution (SGK). VAS, BCTQ scores, and electrophysiological parameters will be evaluated at baseline, and at the 4th and 12th-week follow-ups post-treatment. Electrophysiological measurements will include median nerve distal motor latency (MMNDL), median nerve distal sensory latency (MNSDL), sensory nerve conduction velocity (SNCV), compound muscle action potential (CMAP), and sensory nerve action potential (SNAP) amplitudes.
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 46
- Patients aged 18-65.
- Diagnosed with mild to moderate carpal tunnel syndrome based on electrophysiological studies.
- Received either ultrasound-guided corticosteroid injection or paraffin therapy.
- Symptoms persisting for at least 3 months.
- Diagnosis of other conditions causing neuropathic symptoms (e.g., polyneuropathy, brachial plexopathy, thoracic outlet syndrome).
- History of previous injection or surgery for carpal tunnel syndrome.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Visual Analog Scale (VAS): 0 day, 4th week and 12th week The VAS will be used to measure pain intensity. Patients will mark their pain level on a 10 cm scale, where 0 represents "no pain" and 10 represents the "worst imaginable pain." This will be evaluated at baseline, and at the 4th and 12th weeks post-treatment.
Boston Carpal Tunnel Syndrome Questionnaire Symptom Severity Scale (BCTQ-SSS) 0 day, 4th week and 12th week The SSS assesses the severity of carpal tunnel symptoms such as pain, tingling, and numbness. The total score for this scale ranges from a minimum of 11 to a maximum of 55. A lower score indicates mild or no symptoms, while a higher score suggests more severe symptoms. As the score increases, the severity of symptoms worsens, with a score closer to 55 reflecting a significantly greater impact on daily life.
Boston Carpal Tunnel Syndrome Questionnaire Functional Status Scale (BCTQ-FSS) 0 day, 4th week and 12th week The SSS assesses the severity of carpal tunnel symptoms such as pain, tingling, and numbness. The total score for this scale ranges from a minimum of 11 to a maximum of 55. A lower score indicates mild or no symptoms, while a higher score suggests more severe symptoms. As the score increases, the severity of symptoms worsens, with a score closer to 55 reflecting a significantly greater impact on daily life.
- Secondary Outcome Measures
Name Time Method Median nerve distal motor latency 0 day, 4th week and 12th week It is a finding from electrophysiological evaluation
Motor nerve conduction velocity 0 day, 4th week and 12th week It is a finding from electrophysiological evaluation
Motor nerve action potential amplitude 0 day, 4th week and 12th week It is a finding from electrophysiological evaluation
Median nerve distal sensory latency 0 day, 4th week and 12th week It is a finding from electrophysiological evaluation
Sensory nerve conduction velocity 0 day, 4th week and 12th week It is a finding from electrophysiological evaluation
Sensory nerve action potential amplitude 0 day, 4th week and 12th week It is a finding from electrophysiological evaluation
Trial Locations
- Locations (1)
Beylikdüzü State Hospital
🇹🇷Istanbul, Beylikdüzü, Turkey