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临床试验/NCT04498494
NCT04498494已完成不适用

Role of Electrocardiograms in Risk Stratification and Analysis of the Characteristics of ST Elevation in Acute Myocarditis: A Two-center Study

Yuanli Lei1 个研究点 分布在 1 个国家目标入组 274 人开始时间: 2019年1月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
274
试验地点
1
主要终点
The percentage rate of ST elevation

研究概览

简要总结

The purpose of the present study was to investigate ECG findings of patients with acute myocarditis, ECG findings associated with fulminant myocarditis, and the characteristics of ST-elevation on admission.

详细描述

Acute myocarditis is a severe disease with high mortality rate and various dynamic changes visible on electrocardiograms (ECGs). The aim were to investigate ECG findings in acute myocarditis, ECG findings associated with fulminant myocarditis (FM), and the characteristics of ST elevation at admission. A retrospective analysis of 1814 ECGs was conducted from 274 consecutive patients with acute myocarditis aged ≥13 years, who were hospitalized in two centres between August 2007 and November 2019. All ECG obtained during the hospital course were evaluated by 2 electrophysiologists. A chi-square test was used to evaluate and compare the abnormal ECG findings between the FM and non-FM groups, and multivariate logistic regression analysis was performed to further evaluate ECG findings associated with FM. The Mann-Whitney U test was used to compare the duration of cardiac symptoms before admission for ST elevation at admission.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Retrospective

入排标准

性别
All
接受健康志愿者

入选标准

  • clinical diagnosis of Acute myocarditis
  • complete data of ECG
  • Exclusion Criteria :
  • Incomplete data;
  • a history of congenital heart disease, cardiomyopathy or arrhythmias;
  • myocarditis not being the primary diagnosis for a particular admission;
  • absence of cardiac symptoms.

排除标准

  • 未提供

结局指标

主要结局

The percentage rate of ST elevation

时间窗: through study completion, an average of 2 years

ST elevation was the typical ECG changes of acute myocarditis. The study was to investigate how many patients presented with ST elevation on admission.

次要结局

  • Atrioventricular block, ventricular tachycardia and their correlationwith Fulminant myocarditis (FM)(through study completion, an average of 6 months)

研究者

发起方
Yuanli Lei
申办方类型
Other
责任方
Sponsor Investigator
主要研究者

Yuanli Lei

principal Investigator

Wenzhou Medical University

研究点 (1)

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