Role of Electrocardiograms in Risk Stratification and Analysis of the Characteristics of ST Elevation in Acute Myocarditis: A Two-center Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 274
- 试验地点
- 1
- 主要终点
- The percentage rate of ST elevation
研究概览
简要总结
The purpose of the present study was to investigate ECG findings of patients with acute myocarditis, ECG findings associated with fulminant myocarditis, and the characteristics of ST-elevation on admission.
详细描述
Acute myocarditis is a severe disease with high mortality rate and various dynamic changes visible on electrocardiograms (ECGs). The aim were to investigate ECG findings in acute myocarditis, ECG findings associated with fulminant myocarditis (FM), and the characteristics of ST elevation at admission. A retrospective analysis of 1814 ECGs was conducted from 274 consecutive patients with acute myocarditis aged ≥13 years, who were hospitalized in two centres between August 2007 and November 2019. All ECG obtained during the hospital course were evaluated by 2 electrophysiologists. A chi-square test was used to evaluate and compare the abnormal ECG findings between the FM and non-FM groups, and multivariate logistic regression analysis was performed to further evaluate ECG findings associated with FM. The Mann-Whitney U test was used to compare the duration of cardiac symptoms before admission for ST elevation at admission.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Retrospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •clinical diagnosis of Acute myocarditis
- •complete data of ECG
- •Exclusion Criteria :
- •Incomplete data;
- •a history of congenital heart disease, cardiomyopathy or arrhythmias;
- •myocarditis not being the primary diagnosis for a particular admission;
- •absence of cardiac symptoms.
排除标准
- 未提供
结局指标
主要结局
The percentage rate of ST elevation
时间窗: through study completion, an average of 2 years
ST elevation was the typical ECG changes of acute myocarditis. The study was to investigate how many patients presented with ST elevation on admission.
次要结局
- Atrioventricular block, ventricular tachycardia and their correlationwith Fulminant myocarditis (FM)(through study completion, an average of 6 months)
研究者
Yuanli Lei
principal Investigator
Wenzhou Medical University
