Role of Electrocardiograms in Risk Stratification and Analysis of the Characteristics of ST Elevation in Acute Myocarditis: A Two-center Study
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Myocarditis
- Sponsor
- Yuanli Lei
- Enrollment
- 274
- Locations
- 1
- Primary Endpoint
- The percentage rate of ST elevation
- Status
- Completed
- Last Updated
- 5 years ago
Overview
Brief Summary
The purpose of the present study was to investigate ECG findings of patients with acute myocarditis, ECG findings associated with fulminant myocarditis, and the characteristics of ST-elevation on admission.
Detailed Description
Acute myocarditis is a severe disease with high mortality rate and various dynamic changes visible on electrocardiograms (ECGs). The aim were to investigate ECG findings in acute myocarditis, ECG findings associated with fulminant myocarditis (FM), and the characteristics of ST elevation at admission. A retrospective analysis of 1814 ECGs was conducted from 274 consecutive patients with acute myocarditis aged ≥13 years, who were hospitalized in two centres between August 2007 and November 2019. All ECG obtained during the hospital course were evaluated by 2 electrophysiologists. A chi-square test was used to evaluate and compare the abnormal ECG findings between the FM and non-FM groups, and multivariate logistic regression analysis was performed to further evaluate ECG findings associated with FM. The Mann-Whitney U test was used to compare the duration of cardiac symptoms before admission for ST elevation at admission.
Investigators
Yuanli Lei
principal Investigator
Wenzhou Medical University
Eligibility Criteria
Inclusion Criteria
- •clinical diagnosis of Acute myocarditis
- •complete data of ECG
- •Exclusion Criteria :
- •Incomplete data;
- •a history of congenital heart disease, cardiomyopathy or arrhythmias;
- •myocarditis not being the primary diagnosis for a particular admission;
- •absence of cardiac symptoms.
Exclusion Criteria
- Not provided
Outcomes
Primary Outcomes
The percentage rate of ST elevation
Time Frame: through study completion, an average of 2 years
ST elevation was the typical ECG changes of acute myocarditis. The study was to investigate how many patients presented with ST elevation on admission.
Secondary Outcomes
- Atrioventricular block, ventricular tachycardia and their correlationwith Fulminant myocarditis (FM)(through study completion, an average of 6 months)