Effect of Vitamin D on Enzymes in type 2 Diabetes patients

Phase 2

• Conditions: Type 2 diabetes mellitus; Type 2 diabetes mellitus.

• Registration Number: IRCT20170813035665N2
• Lead Sponsor: Tehran University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 26 August 2019

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

Patients with type 2 diabetes who have35-65 years .
patients take oral hypoglycemic drugs metformin or sulphonylurea.
patients have been diagnosed with at least two years.
Patients do not take supplemental drugs.
patients with BMI less than 30 kg/m2

Exclusion Criteria

do not use vitamin D ,vitamin B6 supplements or diets at least 4-6 weeks before the intervention.

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
GFAT. Timepoint: Before and three months after intervention. Method of measurement: Elisa.;Aldose reductase. Timepoint: Before and three months after intervention. Method of measurement: Elisa.;Hexose amin transferase. Timepoint: Before and three months after intervention. Method of measurement: Elisa.;Glutamin Amido transferase gene expression. Timepoint: Before and three months after intervention. Method of measurement: Real time PCR.;Hexose amin transferase gene expression. Timepoint: Before and three months after intervention. Method of measurement: Real time PCR.;Aldose Reductase gene expression. Timepoint: Before and three months after intervention. Method of measurement: Real time PCR.