Pilot study: Gastric emptying with 13C breath test
Completed
- Conditions
- anorexia verlies van eetlust10003018
- Registration Number
- NL-OMON31414
- Lead Sponsor
- Wageningen Universiteit
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 10
Inclusion Criteria
Apparently healthy, as judged by the subject
Age: Young adults: 18-30 year, Older adults: 60-80 year
Used to eating breakfast (> 5 times per week)
Exclusion Criteria
Weight change of >5kg during the last 2 months
Being on a weight loss diet
On a prescribed diet that interferes with the study foods
Bowel or stomach disorder
Diabetes or thyroid disorder
Food intolerance or allergy for foods that are provided during the study
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>The main study outcome is gastric emptying (and the variation in that<br /><br>measurement). Gastric emptying will be measured with a non-invasive breath<br /><br>test. The subject will come in fasting state to the research centre and ingest<br /><br>the test product which is labelled with 13C. The test foods consist of 2<br /><br>experimental cooked foods, differing in energy content. Each food will be<br /><br>measured in duplicate. Breath samples will be collected before consumption of<br /><br>the food and at 15 minute intervals during 4-6 hours. Breath samples will be<br /><br>analyzed on concentration of 13C. 13C recovery (T1/2 and Tlag) will be used as<br /><br>a measure for gastric emptying. </p><br>
- Secondary Outcome Measures
Name Time Method <p>Secondary, appetite and wellbeing ratings will be measured during the test<br /><br>(Visual Analogue Scales).</p><br>