Impact of Air Pollution and Climate Changes on the Epidemiology of Cardiovascular Disease

Completed

• Conditions: Acute Coronary Syndrome; Particulate Matter Inhalation Injury; Pollution; Exposure; Cardiovascular Diseases; Cardiovascular Risk Factor; Chronic Coronary Insufficiency
• Interventions: Other: Impact of air pollution and climate changes

• Registration Number: NCT04541498
• Lead Sponsor: Medical University of Bialystok

Brief Summary

Despite the fact that the topic of air pollution has been in focus of researchers for many years, there are no big studies that take up the matter of its influence on acute coronary, cerebral syndromes and CVD mortality in Europe. Taking into consideration the scarce number of surveys from Europe the investigators decided to analyze the impact of air pollution on cardiovascular diseases and CVD mortality in Poland.

Detailed Description

Air quality and its impact on health was put in the spotlight since the infamous Great Smog of London. Since then, it became clear that adverse effects are serious and can no longer be ignored. According to the World Health Organization (WHO) estimations, in last year ambient air pollution caused 4,200,000 deaths worldwide. These statistics included a total of 29,165 deaths that were attributed to air pollution in Poland.

The vast of studies are conducted in highly polluted areas, in which patients are exposed to extreme concentrations like China oraz Indie. Taking into consideration the scarce number of surveys from Europe the investigators decided to analyze the impact of air pollution and cardiovascular diseases in Poland.

Data on morbidity and mortality were collected from the National Statistical Office in Poland. The data of air pollutions and gases were obtained from Voivodeship Inspectorate for Environmental Protection. The daily meteorological data were obtained from the Institute of Meteorology and Water Manageme

Study Timeline

• Study Start: 2019-01-01
• Study First Submitted: 2020-08-21
• Study First Submitted QC: 2020-09-01
• Study First Posted: 2020-09-09
• Primary Completion: 2021-08-01
• Status Verified: 2021-09
• Study Completion: 2022-01-01
• Last Update Submitted: 2022-01-06
• Last Update Posted: 2022-01-10

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 150000

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Population of Poland	Impact of air pollution and climate changes	Exposure to short term long term effects of air pollution and climate change
Patients with Acute Coronary and Cerebral Syndromes	Impact of air pollution and climate changes	Exposure to short term long term effects of air pollution and climate change

Primary Outcome Measures

Name	Time	Method
Incidence of acute coronary syndromes	Through study completion, an average of 1 year	Number of acute coronary syndromes related with impact of air pollution
Incidence of cardiovascular mortality	Through study completion, an average of 1 year	Number of cardiovascular deaths related with impact of air pollution
Incidence of acute cerebral syndromes	Through study completion, an average of 1 year	Number of acute cerebral syndromes related with impact of air pollution

Trial Locations

Locations (1)

Department of Invasive Cardiology Medical University of Białystok 24A M. Skłodowskiej-Curie St.; 🇵🇱 Białystok, Poland