CTRI/2021/07/035055尚未招募不适用
Comparative effect of High Frequency Nasal Cannula and Non Invasive Ventilation on the work of breathing and postoperative pulmonary complication after pediatric congenital cardiac surgery : A prospective randomized controlled trial
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- PGIMER
- 入组人数
- 63
- 试验地点
- 1
- 主要终点
- compare the magnitude of decrease in respiratory workload by HFNC, NIPPV and SIPAP as assessed using diaphragmatic thickening fraction and 2D longitudinal strain.
研究概览
简要总结
compares different methods of non invasive ventilation- HFNC, NIV, SIPAP for pediatric cardiac surgery patients post extubation to prevent pulmonary complications. It will also compare their efficacy in terms of work of breathing using ultrasound and also study any side effects.
研究设计
- 研究类型
- Interventional
- 分配方式
- Other
- 盲法
- Not Applicable
入排标准
- 年龄范围
- 30.00 Day(s) 至 4.00 Year(s)（—）
- 性别
- All
入选标准
- •post cardiac surgery belonging to RACHS GROUP 1,2.
排除标准
- •Neonates Preoperative respiratory compromise Preoperative requirement of mechanical ventilation Emergency surgery Residual anatomical defects etc.
- •Diaphragmatic palsy.
结局指标
主要结局
compare the magnitude of decrease in respiratory workload by HFNC, NIPPV and SIPAP as assessed using diaphragmatic thickening fraction and 2D longitudinal strain.
时间窗: at extubation, D1, D2, D3,D4,D5,D6,D7,D8,D9,D10
次要结局
- Changes in oxygenation (P/F ratio; ROX index)(Proportion of patients that require reintubation till 48 hours post extubation and until discharge from ICU.)
研究者
研究点 (1)
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