Comparison of two drugs buprenorphine and dexmedetomedine given intrathecally in pregnant patients undergoing caesarean section.
Not Applicable
- Conditions
- Health Condition 1: Z00-Z99- Factors influencing health status and contact with health servicesHealth Condition 2: O295- Other complications of spinal andepidural anesthesia during pregnancy
- Registration Number
- CTRI/2022/08/044572
- Lead Sponsor
- ESIC Medical College Gulbarga
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Parturients with
1.Singleton pregnancy, scheduled for elective caesarean section under spinal anaesthesia
2.More than 36 weeks of gestation age
3.18-40 years of age
4.Height between 140cm and 180cm
5.BMI less than 32kg/m2,
6.Nil per oral for more than 6 hours
Exclusion Criteria
1.Multiple pregnancy
2.Morbid Obesity (BMI >40)
3.Height <140 cms & >170cms
4.Patients with spinal deformities and those who have undergone previous spine surgeries.
5.Pregnancy related hypertensive disease, preeclampsia, eclampsia.
6.Cardiovascular disease
7.Gestational diabetes requiring insulin.
8.Emergency caesarean sections for maternal or foetal distress.
9.Contraindication to spinal anesthesia.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. To study the onset time and duration of sensory and motor block. <br/ ><br>2. To know the time of first analgesic used. <br/ ><br>3. To assess post-operative pain scores based on visual analog scale (VAS) at 2 hours, 6 hours and 12 hours after the surgery. <br/ ><br>Timepoint: 1. To study the onset time and duration of sensory and motor block in pregnant patients who receive the study drug. <br/ ><br>2. To know the time of first analgesic used. <br/ ><br>3. To assess post-operative pain scores based on visual analog scale (VAS) at 2 hours, 6 hours and 12 hours after the surgery. <br/ ><br>
- Secondary Outcome Measures
Name Time Method 1. To study hemodynamic parameters. <br/ ><br>2. Side effects like hypotension, bradycardia, shivering, vomiting. <br/ ><br>Timepoint: 1. To study hemodynamic parameters till the end of surgery. <br/ ><br>2. Side effects like hypotension, bradycardia, shivering, vomiting during the surgery and postoperative period. <br/ ><br>