Comparison between Buprenorphine skin patch and intravenous Paracetamol for pain relief after major reconstructive plastic surgery
- Conditions
- Health Condition 1: C002- Malignant neoplasm of external lip, unspecified
- Registration Number
- CTRI/2019/03/017947
- Lead Sponsor
- Arghya Maity
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Patients belonging to either sex of age 18-65 years with ASA physical status I and II scheduled to undergo elective major plastic reconstructive surgery under GeneralAnaesthesia.
a)Patient refusal to give consent
b)Patients with evidence of pre-existing pain in nonsurgical site (poly trauma, any fracture, neurological pain etc)
c)Patients with significant cardiac, respiratory, hepatic or renal disorders or any other uncontrolled systemic illness
d)Obesity(BMI >35)
e)History of delirium tremens
f)Pregnancy, Lactation
g)History of allergy to Anaesthetic drugs and analgesics (Paracetamol, Diclofenac, Tramadol) and opioid addiction
h)Those receiving long term analgesic therapy
i)Infection and dermatitis at the site of patch application
j)History of seizures
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. Assessment of Postoperative Pain by Visual Analogue Scale <br/ ><br>2. Need of Rescue Analgesic <br/ ><br>3. Degree of Postoperative Sedation by Ramsay Sedation ScaleTimepoint: Immediate Post operative period, at 2 hrs postoperatively, at 4 hrs postoperatively, at 12 hrs
- Secondary Outcome Measures
Name Time Method Haemodynamic changes ( Heart Rate, Non Invasive Blood Pressure - SBP/DBP/MAP , SpO2, ECG)Timepoint: Immediate Post operative period, at 2 hrs postoperatively, at 4 hrs postoperatively, at 12 hrs postoperatively, at 24 hrs postoperatively, at 36 hrs postoperatively, at 48 hrs postoperatively.