A clinical trial to study pain relief effects of two drugs, buprenorphine and fentanyl which are applied as patches below curved front bone of the shoulder in patients undergoing surgeries involving female reproductive system.
Not Applicable
- Conditions
- Health Condition 1: N00-N99- Diseases of the genitourinary systemHealth Condition 2: N80-N98- Noninflammatory disorders of female genital tract
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Women (Age-18 â?? 60 ).
ASA classes I to III.
Those posted for transabdominal gynecological surgeries performed with pfannenstiel incision.
Exclusion Criteria
History of allergy to opioids.
History of ongoing drug/ alcohol abuse.
Patients who are already using a transdermal opioid patch, dependence on opioids.
Pregnant patients.
Combined epidural block.
Patients with abnormal liver or renal function.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare the postoperative analgesic efficacy between transdermal buprenorphine and transdermal fentanyl after gynecological surgeries using a visual analog scale (VAS) at rest and movement.Timepoint: Visual analog scale (VAS) at rest is recorded at postoperative period of 1st,1.5th,2nd,4th,6th,8th,10th,12th,16th,20th,24th,28th,32nd,36th,40th,44th,48th,72nd hours. <br/ ><br>Visual analog scale (VAS) at movement is recorded at postoperative period of 24th,28th,32nd,36th,40th,44th,48th,72nd hours. <br/ ><br>
- Secondary Outcome Measures
Name Time Method To compare hemodynamic variations such as heart rate (HR), Respiratory rate (RR), systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial pressure (MAP), oxygen saturation (SPO2) between the groups.Timepoint: preoperative period (baseline),postoperative period at 1st,1.5th,2nd,4th,6th,8th,10th,12th,16th,20th,24th,28th,32nd,36th,40th,44th,48th,72nd hours.;To compare the side effects between the groups.Timepoint: postoperative period from 1st to 72nd hours.;To compare the time to rescue analgesia between the groups.Timepoint: Postoperative period from 1st to 72nd hours.;To compare the total amount of rescue analgesic consumption in the postoperative period.Timepoint: postoperative period from 1st to 72nd hours