Comparison of buprenorphine patch with diclofenac intramuscular injection for pain relief following upper abdominal surgery under general anesthesia
Phase 4
- Conditions
- Health Condition 1: null- Upper abdominal surgery under general anesthesia.
- Registration Number
- CTRI/2018/03/012694
- Lead Sponsor
- Department of Anesthesiology
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
ASA grade I or II.
Posted for elective upper abdominal surgical procedure under general anesthesia with likely duration of postoperative hospital stay more than 3 days.
Willing to provide written informed consent.
Exclusion Criteria
Women who are pregnant or breast feeding.
Serious concomitant disease of vital organs, including the liver.
Febrile patient.
Impaired respiratory function.
History of myasthenia gravis.
History of convulsive disorders.
History of delirium tremens.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Visual analog scale (VAS) score. <br/ ><br>Total rescue analgesic dose.Timepoint: Total 8 - hours 4, 8, 12, 24, 36, 48, 60 and 72.
- Secondary Outcome Measures
Name Time Method Ramsay sedation scale (RSS) score. <br/ ><br>Heart rate. <br/ ><br>Systolic and diastolic blood pressure.Timepoint: Total 9 - Baseline (preoperative) and hours 4, 8, 12, 24, 36, 48, 60 and 72.