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临床试验/NL-OMON53691
NL-OMON53691
尚未招募
不适用

The Clock thickens: Morning or evening training for the treatment of NAFLD? - TikTac study

eids Universitair Medisch Centrum0 个研究点目标入组 40 人待定

概览

阶段
不适用
干预措施
未指定
疾病 / 适应症
fatty liver disease
发起方
eids Universitair Medisch Centrum
入组人数
40
状态
尚未招募
最后更新
2年前

概览

简要总结

暂无简介。

注册库
who.int
开始日期
待定
结束日期
待定
最后更新
2年前
研究类型
Observational invasive

研究者

入排标准

入选标准

  • \- Age \>\= 45 years and \<\= 75
  • \- Obese (BMI \> 27 kg/m2\)
  • \- Males and postmenopausal females
  • \- Caucasian
  • \- Hepatic steatosis defined as increased hyperechogenicity of the liver on
  • abdominal ultrasound, CAP score on Fibroscan \> 280, and/or histological signs
  • of steatosis
  • \- Sedentary lifestyle (maximum of 20\*minutes of moderate\-to\-vigorous physical
  • activity per day on less than three days per week)
  • \- Written informed consent

排除标准

  • \- Exclusion criteria for MRI (claustrophobia, pacemaker, metal implants, etc.)
  • \- Any other liver disease than NAFLD/NASH
  • \- Present excessive alcohol use defined as \> 2 units/day
  • \- Recent use (\< 3 months) of antibiotics
  • \- Recent changes in dosages of regular medication (\< 3 months)
  • \- Recent (\< 3 months) weight change (\>5%)
  • \- Recent (\< 3 months) substantial diet changes
  • \- Cardiovascular co\-morbidity defined as heart failure, coronary insufficiency
  • and hypertension in past history
  • \- Comorbidity that contraindicates exercise training and exercise testing or

结局指标

主要结局

未指定

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