Concerted Action Polyp Preventio
Completed
- Conditions
- CancerFamilial Adenomatous Polyposis (FAP)Familial adenomatous polyposis (FAP)
- Registration Number
- ISRCTN83743312
- Lead Sponsor
- ewcastle upon Tyne Hospitals NHS Trust (UK)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 400
Inclusion Criteria
1. Known carriers of familial adenomatous polyposis (FAP), either by molecular genetic analysis or by phenotypic features
2. Over 10 years of age with an intact colon
Exclusion Criteria
1. Already taking Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
2. Partial Resection
3. If over 21 years of age - to take treatment for 1 year only
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. Age at colectomy<br>2. Reduction in size of polyps<br>3. Changes in crypt cell proliferation
- Secondary Outcome Measures
Name Time Method ot provided at time of registration