Efficacy of Blood Flow Restriction with Low-Load Resistance exercise in adults who have risk of symptomatic knee osteoarthritis. (Double-blind randomized controlled trial)
- Conditions
- Strengthening exercise,A four-week, low-load resistance-training program with concurrent application of Blood flow restriction to the exercising limbs to improve knee extensor strength in Adults with risk factors for symptomatic Knee Osteoarthritis.knee osteoarthritisBlood flow restriction,
- Registration Number
- TCTR20210903007
- Lead Sponsor
- Maharat Nakhon Ratchasima Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- nknown
- Sex
- All
- Target Recruitment
- 44
1.Age 40 years old or older
2.at least one of the following risk factors for symptomatic knee Osteoarthritis
2.1 BMI 25 kg/m2 or more
2.2 history of a knee joint injury or surgery
2.3 knee symptoms (pain, aching, or stiffness)
2.4 radiographic knee OA grade 0-1 of Kellgren and Lawrence classification system
3.No contraindication to exercise(AACVPR guideline)
1.regular physical exercise
2.bilateral knee replacements; lower limb surgery in the last six months
3.back, hip or knee problems that affect walking
4.inflammatory joint or muscle disease5.neurologic diagnoses
6.cancer
7.peripheral vascular
disease
8.history of myocardial
infarction or stroke
9.chest pain during exercise or at rest; or need for supplemental oxygen.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1 Repetition Maximum of Knee Extensor Torque at 4 weeks after end of the intervention 1 Repetition Maximum
- Secondary Outcome Measures
Name Time Method 1 Repetition Maximum of Leg Press at 4 weeks after end of the intervention 1 Repetition Maximum,30 seconds chair stand test at 4 weeks after end of the intervention times/30 seconds,KOOS score at 4 weeks after end of the intervention Patient reported outcome using a questionnaire interview