Comparative study between Nifedipine, Progesterone and Ritodrine for maintenance tocolysis in management of preterm labour

Phase 4

Completed

• Conditions: preterm labor; Reproductive Health and Childbirth - Fetal medicine and complications of pregnancy

• Registration Number: ACTRN12616000748415
• Lead Sponsor: Minia University Maternity Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2016-06-07
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: Female
• Target Recruitment: 300

Inclusion Criteria

1-Painful, regular uterine contractions associated with boats of diarrhea or associated with menstrual like cramps.
2- Singleton pregnancy.
3- Intact membranes.
4- Cervical dilation of 3cm or less.
5- The dating of pregnancy confirmed through first trimester ultrasound scanning or last menstrual period.
6- all PTL less than 37 weeks

Exclusion Criteria

Acute attack of preterm labor
Cervical dilatation > 3 cm.
Hypotension (less than 80 mmHg systolic or 50 mmHg diastolic).
Major fetal congenital anomalies.
Unreassuring traces of fetal cardiotocography.
Antepartum hemorrhage or history of recurrent vaginal bleeding
Rupture of membranes.
Multiple pregnancy.
Polyhydraminos.
Chorioamnionitis.
Unexplained pyrexia.
Medical disorders i.e. diabetes, cardiac disease.
Sensitivity or contraindication to nifedipine or beta-agonist.
Other tocolytic therapy during this pregnancy.

Study & Design

• Study Type: Interventional
• Study Design: Not specified