An interventional study to assess the effectiveness of single perineural injection of platelet rich plasma on nerve function with special emphasis on nerve function of Hansens disease with truncal (mixed) neuropathy

AIIMS Bhopal0 个研究点目标入组 30 人开始时间: 待定最近更新: 2024年6月24日

试验速览

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•1. Known case of Hansen’s disease on or post treatment with Multi drug therapy
•2. Age: =18 years
•3. Patients of Hansen’s disease with peripheral neuropathy involving Ulnar and/ or
•Common Peroneal Nerve with residual impairment
•4. Willingness to participate in study (informed written consent)
•5. Willingness to forego any other concomitant treatment modality

•1. Hansen’s disease diagnosed for more than three years duration.
•2. Signs of active inflammation or abscess around the Ulnar or Common Peroneal
•3. Diagnosed case of active lepra reaction
•4. Infection at the site of injection
•5. Reduced range of motion of knee, elbow, wrist or ankle
•6. Abnormal radiograph of elbow joint and knee joint of the affected side
•7. Received local steroid injection within 6 months, NSAIDS within one week prior
•to intervention or on systemic steroids more than 20 mg daily
•8. Abnormal haemoglobin or blood count (platelet count < 50x 109
•g/dl,Mean platelet volume >12.3 fl)
•9. Use of anti-platelet medications
•10. Uncontrolled Diabetes Mellitus (FBS >125 mg/dl or PPBS >200 mg/dl)
•11. Known case of severe cardiac, liver or renal disease
•12. Pregnancy or lactation
•13. Unwillingness to participate in study

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