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Clinical Trials/NCT03540797
NCT03540797
Unknown
Not Applicable

The Roles of MDSCs (Myeloid-derived Suppressor Cells) in Adult Patients With Sepsis.

Chung Fu-Tsai1 site in 1 country125 target enrollmentJuly 1, 2015
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ConditionsSepsis

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Sepsis
Sponsor
Chung Fu-Tsai
Enrollment
125
Locations
1
Primary Endpoint
Survival of Intensive care unit (ICU) stay
Last Updated
7 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSitesSimilar Trials

Overview

Brief Summary

This study is designed for septic patients, to isolate MDSCs and the correlation of prognosis of sepsis. The purpose of this study hopes to explore the phenomenon and possible mechanisms of MDSCs in patients with severe sepsis.

Registry
clinicaltrials.gov
Start Date
July 1, 2015
End Date
December 31, 2023
Last Updated
7 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
Chung Fu-Tsai
Responsible Party
Sponsor Investigator
Principal Investigator

Chung Fu-Tsai

Attending physician

Chang Gung Memorial Hospital

Eligibility Criteria

Inclusion Criteria

  • •Patients must have known origin of infection .
  • •Systemic inflammatory response syndrome.

Exclusion Criteria

  • •age less than 18 years
  • •pregnancy
  • •known anaphylactoid reaction to colloid fluids
  • •a life expectancy less than 24 hours,
  • •inability to provide informed, written consent
  • •Patients receiving nephrotoxic drugs,
  • •admitted to the hospital following a surgical procedure,
  • •sepsis more than 72 hours when screening .

Outcomes

Primary Outcomes

Survival of Intensive care unit (ICU) stay

Time Frame: 28 days

Secondary Outcomes

  • In hospital survival(90 days)

Study Sites (1)

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