NCT01224223已完成不适用
Myeloid Suppressors in Inflammation
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- To identify and characterize specific cell types (human dendritic cells, myeloid-derived suppressor cells and T lymphocytes) that are present in acute and chronic asthma.
研究概览
简要总结
Myeloid-derived suppressor cells (MDSC) have been studied for their ability to suppress T cell responses in vivo and in vitro. As a result, MDSC can regulate cellular responses to chronic inflammatory conditions such as cancer, leading to the induction of tolerance and, ultimately, tumor escape from immune surveillance.
研究设计
- 研究类型
- Observational
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- •Use of systemic corticosteroids within the previous two weeks.
- •Pregnant and/or lactating females.
- •Current tobacco use.
- •Severe psychiatric illness.
- •Current illicit substance abuse or dependence and/or abuse of alcohol.
- •Current use of anti-microbial medications.
- •Primary or secondary immunodeficiency.
- •Any clinically significant uncontrolled medical condition that would put the patient's safety at risk.
结局指标
主要结局
To identify and characterize specific cell types (human dendritic cells, myeloid-derived suppressor cells and T lymphocytes) that are present in acute and chronic asthma.
时间窗: one year from start of study
次要结局
未报告次要终点
研究者
Richard Lockey
principal investigator
University of South Florida
研究点 (1)
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