Vibrotactile Stimulation of the Larynx to Treat Unexplained Chronic Cough

University of Minnesota1 site in 1 country60 target enrollmentJuly 13, 2021

ConditionsCough

Overview

Researchers will test the effect of non-invasive vibrotactile stimulation of the larynx on symptom severity of unexplained chronic cough.

Registry

clinicaltrials.gov

Start Date

July 13, 2021

End Date

December 30, 2027

Last Updated

8 months ago

Study Type

Interventional

Study Design

Single Group

Sex

All

Sponsor

Responsible Party

Sponsor

•Adults aged 18-88
•\>8 weeks of cough
•Cough visual analogue scale (VAS): Rating of 30 or greater on a 0-100 cough severity scale
•Ability to provide informed consent and independently complete questionnaires
•Ability to read and speak English

•Electronic implants (e.g., pacemaker)
•Currently doing speech therapy for cough
•Contraindications to safe or effective VTS device use
•No regular access to wifi internet Neuromuscular impairment that may affect cough/laryngeal sensation and/or function (e.g., multiple system atrophy, Parkinson, CVA, vocal fold paralysis or paresis)
•Untreated carotid disease
•BMI \> 40 (for transmission of VTS through soft tissue)
•Current or recent (quit \< 3 months ago) smoking
•Known currently infectious cause for cough (e.g., TB, pertussis, COVID)
•History of known or suspected aspiration pneumonia
•Diagnosis or clinical suspicion of chronic obstructive pulmonary disease (COPD)