DRKS00003185已完成未知
euroendocrinological effects of lithium and citalopram on the cortisol regulation of patients with major depression - LiCo study
Klinik für Pschiatrie und PsychotherapieUniversitätsklinikums Carl Gustav Carus an derTechnischen Universität Dresden0 个研究点目标入组 62 人开始时间: 2011年7月6日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 62
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Non-randomized controlled study
- 盲法
- Open (masking not used)
入排标准
- 年龄范围
- 18 Years 至 75 Years（—）
- 性别
- All
入选标准
- •diagnosis of a major depression according to DSM-IV, SCID I confirmed; at least 15 points on the Hamilton Rating Scale for Depression (21 item version); indication for a antidepressive pharmacotherapy independently of the study; oral and written informed consent; ability to give informed consent
排除标准
- •manic or hypomanic episode in history (bipolar disorder); psychotropic medication within one wek prior to enrollment (one week wash out if neccessary); 20 mg/d diazepam or an equivalent dosage of another bezodiazepine are allowed prior and during the study; severe medical condition; conditions that contraindications to SSRIs or lithium or to the Dex/CRH test (e.g. severe renal dysfunction, severe cardial dysfunction, dysfunction of glucocorticoid or mineralocorticoid regulation); pregnancy; breast feeding; unsecure contraception; other axis I diagnoses beside the affective disorder; substance dependency
研究者
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