ACTRN12617001365358
Recruiting
N/A
A randomized clinical trial comparing preoperative continuation versus cessation of angiotensin converting enzyme inhibitors and angiotensin receptor blockers in patients undergoing elective, noncardiac surgery at a major tertiary hospital.
Metro South Health - Princess Alexandra Hospital0 sites666 target enrollmentSeptember 27, 2017
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- Metro South Health - Princess Alexandra Hospital
- Enrollment
- 666
- Status
- Recruiting
- Last Updated
- 3 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Adult (\>18 years of age)
- •Non\-pregnant
- •Patients at Princess Alexandra Hospital (Brisbane, Queensland)
- •Attendance at preadmission clinic at least twenty\-four hours prior to day of surgery
- •Elective surgery
- •Planned general anaesthetic
- •Prescribed an ACEi or ARB on a stable dose for the previous twenty\-eight days
Exclusion Criteria
- •Systolic blood pressure greater than 180 mmHg noted on preadmission clinic visit
- •Cardiac surgery
- •Transplant surgery
- •Cognitive impairment or other neurological disorders resulting in patients lacking capacity to provide informed consent and a legally authorized substitute decision maker (power of attorney or statutory health attorney or appointed guardian) does not exist or is unavailable to provide informed consent.
Outcomes
Primary Outcomes
Not specified
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