Diffusion-tensor Imaging in Brain Tumors Evaluation
- Conditions
- MRIDiffusion Tensor ImagingTractography
- Interventions
- Diagnostic Test: MRI
- Registration Number
- NCT05261724
- Lead Sponsor
- George Emil Palade University of Medicine, Pharmacy, Sciences and Technology of Targu Mures
- Brief Summary
Primary and secondary brain tumors are challenging pathologies regarding diagnosis and treatment. MRI is widely used in the imaging evaluation and surgical planning, due to its spatial resolution and ability of tissular characterization.
In this study patients with suspected brain tumors, confirmed by routine MRI evaluation (T1, T2, T2\*, FLAIR, T1 with contrast sequences) will undergo DWI and DTI evaluation. By analyzing collected data from MRI evaluation and patient records regarding surgical and histopathological data our aim is to investigate derived imaging biomarkers with impact in the surgical planning and rehabilitation of the patients.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 100
- brain tumors confirmed by routine MRI evaluation
- surgical treatment with histopathological diagnosis
- MRI contraindications
- past or present neurological or neurosurgical condition, beside the tumor
- pregnancy
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Patients with primary brain tumors MRI - Patients with secondary brain tumors MRI -
- Primary Outcome Measures
Name Time Method Tract damage 3 months Assess the damage of tracts at baseline preoperative
- Secondary Outcome Measures
Name Time Method Craniotomy size 3 months Assess the size of craniotomy in patients with postoperative CT follow-up
Trial Locations
- Locations (1)
SCJU Mures
🇷🇴Targu Mures, Mures, Romania