Contribution of Diffusion Tensor Imaging and Tractography in Primary and Secondary Brain Tumors Evaluation
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Tract damage
研究概览
简要总结
Primary and secondary brain tumors are challenging pathologies regarding diagnosis and treatment. MRI is widely used in the imaging evaluation and surgical planning, due to its spatial resolution and ability of tissular characterization.
In this study patients with suspected brain tumors, confirmed by routine MRI evaluation (T1, T2, T2*, FLAIR, T1 with contrast sequences) will undergo DWI and DTI evaluation. By analyzing collected data from MRI evaluation and patient records regarding surgical and histopathological data our aim is to investigate derived imaging biomarkers with impact in the surgical planning and rehabilitation of the patients.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •brain tumors confirmed by routine MRI evaluation
- •surgical treatment with histopathological diagnosis
排除标准
- •MRI contraindications
- •past or present neurological or neurosurgical condition, beside the tumor
- •pregnancy
结局指标
主要结局
Tract damage
时间窗: 3 months
Assess the damage of tracts at baseline preoperative
次要结局
- Craniotomy size(3 months)
研究者
Mihail Porutiu
Phd student
George Emil Palade University of Medicine, Pharmacy, Sciences and Technology of Targu Mures