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临床试验/NCT07240090
NCT07240090尚未招募不适用

Relation of Craniovertebral Angle With Lumbar Proprioception and Trunk Muscles Strength in Patients With Cervical Radiculopathy

Basma Ashraf Ali Mohamed1 个研究点 分布在 1 个国家目标入组 64 人开始时间: 2025年11月18日最近更新:
适应症

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
64
试验地点
1
主要终点
Craniovertebral angle

研究概览

简要总结

The study aimed to

  • Investigate the relation of cranio-vertebral angle with lumbar proprioception in patients with cervical radiculopathy.
  • Investigate the relation of cranio-vertebral angle with trunk muscles strength in patients with cervical radiculopathy. Cervical radiculopathy is a condition that causes neck pain radiating to the arm due to nerve root compression. The study seeks to explore whether posture and trunk control are affected in these patients. Participants will be assessed for craniovertebral angle, lumbar proprioception, and trunk muscle strength using standardized physical therapy evaluation methods. The findings may help in understanding postural and neuromuscular changes associated with cervical radiculopathy and improve rehabilitation programs

详细描述

Cervical radiculopathy is a major disabling condition characterized by neck pain radiating to one or both of the upper extremities . Epidemiological data suggest that CR affects approximately 83 per 100,000 individuals annually, with peak incidence occurring between ages 40 and 50 years and a lifetime prevalence of 3.5% in the general population .

Cervical radiculopathy is a common neurological condition caused by nerve root compression. Cervical radiculopathy is frequently associated with neck pain and includes tingling, numbness, or discomfort in the arm, upper back, and upper chest with or without an associated headache. Frequent headaches, scapular pain, and sensory, motor and reflex dysfunction in the upper extremities are often associated with cervical radiculopathy. These symptoms can be extended to the neck muscles, zygapophyseal joints, intervertebral discs, nerve roots, or trunk. In addition, higher levels of self-reported disability are reported among patients with neck pain and cervical radiculopathy .

The underlying cervical spinal pathologies, including disc herniation, osteophyte formation, and spinal canal stenosis, are widely recognized as common precipitating factors for nerve root compression or inflammation in CR . Approximately 70-75% of CR cases co-occur with degenerative changes, while 20-25% are attributed to intervertebral disc herniation. Repetitive overloads and micro-injuries lead to spinal canal narrowing and disc degeneration via the hypertrophy of the spinal joints and the encroachment of surrounding structures. This degeneration promotes osteophyte formation, elevated levels of local prostaglandins causing inflammation near the dorsal root ganglion .

According to the latest Global Burden of Disease data, neck pain is the fourth leading cause of years lived with disability, following only back pain, major depressive disorder, and arthralgias .Over the past ten years, there has been an increase of 19% in both the prevalence of cervical spine pain and the number of years people have been disabled globally.

Forward head posture (FHP) is a poor habitual neck posture resulting from the prolonged inherence of a static awkward position .It is associated with muscle imbalance and joint decentration, particularly at the atlanto-occipital joint, C4-C5 segment, glenohumeral joint, cervicothoracic joint, and T4-T5 segment . FHP has been viewed as a cervical sagittal imbalance and is defined as an increase in C2-C7 sagittal vertical alignment (SVA). Lately, cervical sagittal vertical alignment has been found to be the most relevant parameter of cervical sagittal balance in distinguishing symptomatic subjects from asymptomatic subjects .

研究设计

研究类型
Observational
观察模型
Other
时间视角
Cross Sectional

入排标准

年龄范围
30 Years 至 55 Years(Adult)
性别
All
接受健康志愿者
否

入选标准

  • •Patients with cervical radiculopathy with ≥3 months history of neck pain radiating to only one upper extremity (unilateral)
  • •Patients with forward head posture and craniovertebral angle <50°
  • •Age between 30 and 55 years
  • •Body mass index (BMI) between 18 and 29.9 kg/m²

排除标准

  • •Cervical myelopathy
  • •Acute cervical radiculopathy
  • •Neck pain without radiculopathy
  • •Diabetic neuropathy
  • •Previous cervical surgery
  • •Cervical trauma
  • •Entrapment neuropathies in the upper limbs
  • •Rheumatoid arthritis
  • •Tumors or infections involving the cervical or lumbar spine
  • •Acute or chronic lumbar radiculopathy
  • •Vertebral fractures
  • •Lumbar spinal stenosis
  • •Cauda equina syndrome
  • •Previous lumbar surgery
  • •Lumbar spondylolisthesis

结局指标

主要结局

Craniovertebral angle

时间窗: baseline

The craniovertebral angle will be measured using digital photography to assess forward head posture in patients with cervical radiculopathy. The assessment of the FHP will be carried out by measuring the craniovertebral angle. Standing cervical posture alignment will be measured with photogrammetry, which provides a valid and reliable indicator of forward head posture using the CVA . A smartphone will be mounted on a tripod and positioned 1.5 meters away from the participant, with the height adjusted to the level of the participant's shoulder. Adhesive markers will be placed on a participant's C7 spinous process and tragus of the ear. The therapist will observe the participant from the lateral side while standing and then will take a picture of the participant from a fixed distance 1.5 meters

Lumbar proprioception

时间窗: baseline

Lumbar joint position sense will be assessed once by measuring the difference between the target and reproduced trunk flexion angle at 30 degrees using an isokinetic device to evaluate proprioceptive accuracy in patients with cervical radiculopathy The Biodex System 3 Pro Isokinetic Dynamometer (Biodex Medical Systems, Shirley, NY, USA) will be used to assess lumbar proprioception. The dynamometer with a specific reclining back attachment is designed to assess the lumbar region's repositioning accuracy. Its validity is ICC = 0.99 and reliability is ICC = 0.99 for evaluating joint position sensation. Testing active repositioning of the lumbar spine is at 30°/s During the training, the participants will be instructed to maintain a specific spinal range of motion, which range from neutral extension of the lumbar spine to 30° flexion. This range is chosen because of the ability of all participants to do it .

Tunk muscles strength

时间窗: baseline

Trunk flexor and extensor muscle strength will be measured once using an isokinetic dynamometer at two angular velocities (60°/s and 120°/s) to evaluate muscle performance in patients with cervical radiculopathy The Biodex System 3 Pro (Biodex Medical Systems IIVC;Shirley , Shirley, NY, USA) will be used to conduct the isokinetic and isometric trunk strength test . Peak torque will be the primary outcome to be asessed in trunk isokinetic variables, peak torque indicates the highest muscle force output through the range of motion and reflects muscle strength .The trunk range of movement will be limited at 50°, with 30° (-30°) of trunk flexion and 20° (+20°) of trunk extension. It will started from the flexion position and will be performed with 60°/s and 120°/s angular velocities

次要结局

未报告次要终点

研究者

发起方
Basma Ashraf Ali Mohamed
申办方类型
Other
责任方
Sponsor Investigator
主要研究者

Basma Ashraf Ali Mohamed

Demonstrator

Cairo University

研究点 (1)

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