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Ademhalingsstudie naar de interactie tussen remifentanil en propofol in gezonde vrijwilligers.

Recruiting
Conditions
BreathingBISHealthy volunteersRemifentanilPropofolAdemhalingGezonde vrijwilligersPK-PD
Registration Number
NL-OMON19898
Lead Sponsor
eiden University Medical Centre
Brief Summary

/A

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
Not specified
Target Recruitment
24
Inclusion Criteria

1. Healthy volunteers of either sex;

2. Age 18-45 years.

Exclusion Criteria

1. BMI > 35;

2. Presence of any medical disease;

Study & Design

Study Type
Observational non invasive
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
1. Ventilation (l/min);<br /><br>2. EEG monitoring via BIS;<br /><br>3. Bloodsampling for propofol concentrations.<br>
Secondary Outcome Measures
NameTimeMethod
1. Cardiac output;<br /><br>2. Heartrate;<br /><br>3. Saturation.
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