A Double Blind, Randomised Controlled Trial of Pre-incision Wound Infiltration Using Diclofenac Versus Bupivacaine for Post-operative Pain Relief in Open Thyroid and Parathyroid Surgery

Not Applicable

Completed

• Conditions: Efficacy of pain control in patient undergone Open thyroid or parathyroid surgery; Randomised controlled trial; Wound infiltration; parathyroid surgery; Bupivacaine; Diclofenac; thyroid surgery

• Registration Number: TCTR20180925008
• Lead Sponsor: Self Sponsored

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2017-11-08
• Study Start: 2018-09-25
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 94

Inclusion Criteria

(i) aged 18 and above
(ii) underwent open thyroid or parathyroid surgery
(iii) able to give informed consent.

Exclusion Criteria

(i) previous neck incision over the site of intended incision
(ii) history of allergy, sensitivity or contraindicated to local anaesthetic, NSAID, opioids and paracetamol
(iii) cervical lymphadenopathy needing radical neck dissection
(iv) co-morbidities of renal failure, liver failure, history of peptic ulcer, bronchial asthma, clotting disorder
(v) poorly controlled diabetes mellitus, hypertension and heart disease
(vi) unable to provide informed consent

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Post-operative pain score Within 24 hours post-opeatively Numeric rating scale -11

Secondary Outcome Measures

Name	Time	Method
duration to first analgesia Within 24 hours post-operatively minutes,total analgesic agent usage in 24 hours post-operative period, Within 24 hours post-operatively mg,rescue tramadol usage Within 24 hours post-operatively mg,total cost of analgesic agent used in in 24 hours post-operativ Within 24 hours post-operatively Ringgit Malaysia