to check the effect of gum treatment on the blood lipid levels of individuals having altered lipid levels
- Conditions
- chronic periodontital disease with hypercholesteromia
- Registration Number
- CTRI/2016/03/006700
- Lead Sponsor
- Jasmine Malhotra
- Brief Summary
The patients meeting the inclusion criteria were divided into 2 groups: test and control group. the test group received complete periodontal therapy consisting of supra ginval, sub gingival scaling, root planing and open flap debridement. the control group underwent only supragingival scaling. the clinical periodontal parameters, lipid profile parameters, resistin levels, BMI and waist hip ratio were evaluated at baseline and 3 months post periodontal therapy.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 30
- The inclusion criteria consisted of patients having altered lipid profile i.e. the patients having hypercholesterolemia and falling under the moderate risk or low risk and those that can be treated by Therapeutic Lifestyle Changes (TLC) only (as given by American heart association ATP III guidelines.
- Patients should not be on any cholesterol lowering drugs and otherwise systemically healthy patients within the age group of 30-65 yrs.
- Patients with pocket probing depth ≥5 mm with clinical attachment loss of ≥1 mm (≥2quadrants).
- Presence of a minimum of 20 teeth was obligatory for inclusion in the clinical trial.
patients having history of any systemic disease like renal, hepatic, cardiac, diabetes, immunological or haematological disorders with contra-indication for minor oral surgical procedure, pregnant women, patients on chemotherapeutic agents in the previous 3 months or oral antiseptics in the previous month, previous periodontal treatment over the past six months, patients on estrogen replacement therapy and patients on folic acid or vitamin B6 or B12.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method decrease in clinical periodontal parameters and serum lipid profile parameters baseline and 3 months
- Secondary Outcome Measures
Name Time Method decrease in resistin, BMI and waist-hip ratio baseline and 3 months
Trial Locations
- Locations (1)
manipal college of dental sciences
🇮🇳Udupi, KARNATAKA, India
manipal college of dental sciences🇮🇳Udupi, KARNATAKA, Indiajasmine malhotraPrincipal investigator7760598367jmjasminemalhotra@gmail.com