Skip to main content
Clinical Trials/NCT06260202
NCT06260202
Completed
Not Applicable

Nutrition Under Noninvasive Ventilation in Critically Ill Patients: a Retrospective Monocentric Analysis

Università degli Studi del Piemonte Orientale Amedeo Avogadro1 site in 1 country112 target enrollmentMarch 1, 2024

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Noninvasive Ventilation
Sponsor
Università degli Studi del Piemonte Orientale Amedeo Avogadro
Enrollment
112
Locations
1
Primary Endpoint
Caloric and protein gap
Status
Completed
Last Updated
last year

Overview

Brief Summary

Even though nutrition is a fundamental component of Intensive care unit (ICU) therapy, critically ill patients are frequently malnourished, a factor well known for its strong association with a higher risk of complications, prolonged ICU/hospital length of stay, and greater ICU readmission and mortality rates. Noninvasive ventilation (NIV) use has increased considerably over the past twenty years, making this supportive technique a keystone of acute respiratory failure (ARF) treatment. In this setting, respiratory support is provided through an interface, usually a mask or a helmet, that frequently represents an important obstacle to nutrition delivery, making oral intake impossible and posing the necessity to start enteral (EN) or parenteral nutrition (PN). Moreover, while critical care guidelines regarding nutritional management of patients receiving mechanical ventilation (MV) are well established, data and recommendations about the appropriate nutritional support to patients in NIV are still very limited. Due to this limited data, we want to describe characteristics and nutritional management of patients undergoing NIV in ICU, and to evaluate the difference between the mean caloric and protein intake of these patients and the recommended caloric and protein target for critically ill patients. Secondarily, we want to evaluate the difference of the caloric and protein intake among groups of patients undergoing different nutritional modality and to assess potential associations of the nutritional characteristics with patient outcomes.

Registry
clinicaltrials.gov
Start Date
March 1, 2024
End Date
May 31, 2024
Last Updated
last year
Study Type
Observational
Sex
All

Investigators

Sponsor
Università degli Studi del Piemonte Orientale Amedeo Avogadro
Responsible Party
Principal Investigator
Principal Investigator

Francesca Moretto

Principal Investigator

Università degli Studi del Piemonte Orientale Amedeo Avogadro

Eligibility Criteria

Inclusion Criteria

  • Adult patients;
  • Admission to the Intensive Care Unit of Maggiore della Carità University Hospital from March 1st 2020 to February 28th 2023;
  • Noninvasive ventilation treatment for acute respiratory failure of any cause;
  • Duration of noninvasive ventilation treatment of more than two days;
  • Informed consent signed.

Exclusion Criteria

  • Patients under 18 years of age;
  • Duration of noninvasive ventilation treatment of less than two days.

Outcomes

Primary Outcomes

Caloric and protein gap

Time Frame: At ICU discharge, a median of six days

to evaluate the difference between the mean caloric and protein intake of these patients and the recommended caloric and protein target for critically ill patients for every day of ICU stay

Secondary Outcomes

  • Nutrition modalities outcomes(At ICU discharge, a median of six days)

Study Sites (1)

Loading locations...

Similar Trials