Comparing the effect of locally delivered drugs- chitosan and tetracyline in addition to scaling and root planing in patients with type 2 diabetes mellitus
- Conditions
- Health Condition 1: E119- Type 2 diabetes mellitus without complications
- Registration Number
- CTRI/2023/10/058766
- Lead Sponsor
- ishmitha Shetty
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
1)Patients with type-2 diabetes with HbA1c = 7.
2)Patients who agree to participate in the study by signing the informed consent.
3)Age = 30 years, irrespective of the gender.
4)Patients diagnosed with stage II and stage III grade B periodontitis having completed active periodontal treatment at least 3-6 months prior and are receiving regularly supportive periodontal therapy (while exhibiting residual pockets of = 5 mm.
5)Full Mouth Plaque Score- less than 25%
6)Full Mouth Bleeding Score- less than 25%
Patients having systemic diseases other than diabetes mellitus.
2) Use of drugs such as anti-inflammatory, immune-suppressants, calcium antagonist, anti-epileptic.
3) Use of antimicrobial mouth rinses in the preceding 2 months
4) Smokers
5) Patients who were neither on antibiotic therapy nor had undergone any periodontal therapy in the past 6 months were included in the study
6) Restorations and caries in the area to be treated.
7) History of allergy of tetracycline or chitosan.
8) Pregnant or lactating women
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Reduction in pocket probing depth, gain in clinical attachment level and reduction in perio-pathogensTimepoint: At baseline and at 6 months
- Secondary Outcome Measures
Name Time Method Overall improvement in oral healthTimepoint: 3 MONTHS