NL-OMON38933CompletedNot Applicable
The role of the gut MIcrobiota in the SyStemic Immune respONse during human endotoxemia - MISSION-2
Conditions
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Academisch Medisch Centrum
- Enrollment
- 16
Study Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Interventional
Eligibility Criteria
- Ages
- 18 to 99 (—)
Inclusion Criteria
- •1. Healthy (medical history, no use of medication; normal physical examination, ECG and laboratory tests)
- •2. Male between 18 and 35 years of age
- •3. Normal defecation pattern
Exclusion Criteria
- •1. Recent major illness or chronic medical illness
- •2. History of malignancy
- •3. Gastrointestinal and liver diseases
- •4. Known positive test for hepatitis B or C or HIV
- •5. Smoking; drug abuse; alcohol abuse
- •6. Clinically relevant ECG abnormality
- •7. Subject has received an investigational product within three months of day 1 of the current study
- •8. Use of prescription or non-prescription drugs
- •9. Recent (< 12 months) use of antibiotics
- •10. Allergy to antibiotics
- •11. Difficultly in donating blood or limitied accessibility of a vein in left or right arm.
- •12. Subject has donated more than 350 mL of blood in last 3 months
- •13. Difficulty swallowing pills
- •14. Body mass index >28 kg/m2
Investigators
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