Het effect van antibiotica en de darmflora op afweerreacties
- Conditions
- Endotoxemia
- Registration Number
- NL-OMON27487
- Lead Sponsor
- Academic Medical Centre, Amsterdam
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 16
Inclusion Criteria
1. Healthy, as determined by a responsible physician, based on a medical evaluation
including medical history, physical examination and laboratory tests
Exclusion Criteria
1. Subject has had a major illness in the past 3 months or any significant chronic
medical illness
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Cytokine production in blood
- Secondary Outcome Measures
Name Time Method Activation of coagulation<br /><br>Composition of gut microbiota
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms link gut microbiota to systemic immune responses in human endotoxemia?
How do antibiotics alter gut flora and subsequent immune activation in endotoxemic patients?
What biomarkers correlate with immune modulation outcomes in NL-OMON27487 trial?
Are there specific gut microbial taxa associated with improved endotoxemia management strategies?
What combination therapies show promise alongside microbiota-targeted interventions for endotoxemia?