Comparison of duration of postoperative analgesia after lateral quadratus lumborum block versus subcostal transversus abdominis plane block in laparoscopic cholecystectomy- A randomised controlled study
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 64
- 试验地点
- 1
- 主要终点
- To assess postoperative analgesia using VAS score
研究概览
简要总结
| Laparoscopic surgery is nowadays a |
| common technique used in variety of abdominal surgeries including |
| cholecystectomy, appendicectomy, inguinal hernia repair, hemicolectomy etc. Eventhough |
| post-operative pain after laparoscopy is lesser than in open operative |
| techniques, the abdomen stiffness due to the pneumoperitoneum (created as a |
| step of the laparoscopic approach) and operative manipulations may cause severe postoperative pain that |
| will affect the patient satisfaction and the outcome of the surgery.1 |
The various modes of pain management include parenteral administration of opioids, NSAIDs, wound infiltration with local anaesthetics, neuraxial anaesthesia, peripheral nerve blocks.etc. Multimodal approach provide better pain control. But these techniques are associated with drawbacks- opioids are associated with vomiting, pruritus, oversedation and respiratory depression;NSAIDs can cause nausea, vomiting and gastric irritation,etc. Regional anesthesia techniques can be used as sole anesthetic technique or adjuvant to general anesthesia for intra operative and postoperative analgesia.2
The transversus abdominis plane (TAP)block, first introduced by Rafi in 2001 as a landmark-guided technique via the triangle of Petit to achieve a field block. It involves the injection of a local anesthetic solution into the plane between the internal oblique muscle and transversus abdominis muscle.The local anesthetic spread in this plane can block the neural afferents and provide analgesia to the anterolateral abdominal wall, as the thoracolumbar nerves originating from the T6 to L1 spinal roots run into this plane and supply sensory nerves to the anterolateral abdominal wall.3USG facilitates accurate placement of block needle and real time deposition of local anaesthetic, increasing both margin of safety and block quality.4
Quadratus lumborum block is a block of the posterior abdominal wall, “interfascial plane block†which is performed under ultrasound guidance. It was described by anaesthesiologist Dr. Rafael Blanco as a variant of TAP block in 2007.Today four types of QL block are performed which differ by the site of drug application. These are QLB1or lateral QLB, QLB2 or posterior QLB, QLB3 or anterior /transmuscular QLB and QLB4 or intramuscular QLB. QLB1 or lateral QLB implies the application of local anaesthetics on the lateral side of the QLM on the area of its contact with transverasalis fascia, at the level where tranversus abdominis muscle taper off to its aponeurosis.5
This study is aimed to compare and evaluate the analgesic effectiveness between Lateral QLB and subcostal TAPB after laparoscopic cholecystectomy.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Outcome Assessor Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)(—)
- 性别
- All
入选标准
- •Patients who are willing to give informed consent.
- •Patients of age 18-60 years.
- •ASA grade 1 &
- •Patients with BMI 18.5-
- •Patients undergoing laparoscopic cholecystectomy.
排除标准
- •Patient refusal.
- •Patients with history of coagulopathy.
- •Patients with history of allergic to local anaesthetic.
- •Patients with severe systemic diseases.
- •Psychiatric illness.
- •Chronic medication taking for pain.
- •Localized infection over injection point.
结局指标
主要结局
To assess postoperative analgesia using VAS score
时间窗: To assess VAS score at 30 minutes, 60minutes, 1hour, 2hour, 4hour,8hour,12hour,24hour postoperatively
次要结局
- Need of rescue analgesia(Time of requirement of first dose od Inj.Tramadol 2mg per kg body weight)
- Hemodynamic parameters like Heart rate, blood pressue and spO2(Assess heart rate, blood pressure, spO2 at 30 minutes, 60minutes, 1hour, 2hour, 4hour,8hour,12hour,24hour postoperatively)
研究者
Dr.Riya Ravindran
Bangalore Medical College and Research Institute
