The effect of activity on insulin sensitivity and lipid metabolim in sedentary people.

Completed

• Conditions: high glucose levels; insulin resistance; 10018424

• Registration Number: NL-OMON36677
• Lead Sponsor: niversiteit Maastricht

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 6 May 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 23

Inclusion Criteria

- Person, 18-60 years old
- BMI 20.0 - 30.0 kg/m2
- Exercise: maximum 1 hour/ week, <= 2x/week; (in the past 3 months)

Exclusion Criteria

- Cardiovascular diseases
- Known diabetes mellitus type 1 and 2 or fasting glucose > 6.9 mmol/L
- Other diseases that make physical activity difficult
- Alcohol, a mean of > 2 consumptions/day (in the past 3 months)
- Illegal drug use and cannabis use (in the past 3 months)
- Medication use, other than contraception (in the past 3 months)
- Triglycerides > 3.0 mmol/L

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The change in<br /><br>- glucose<br /><br>- insuline<br /><br>of the activity program walking compared to sitting, and the activity program<br /><br>sitting/biking compared to sitting.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>- Area under the curve of glucose and insuline of the activity program walking<br /><br>compared to sitting, and the activity program sitting/biking compared to<br /><br>sitting.<br /><br>- Total cholesterol, HDL, LDL, triglyceriden, apoB en apoA of the activity<br /><br>program walking compared to sitting, and the activity program sitting/biking<br /><br>compared to sitting.<br /><br>- The amount of minutes sitting/ walking/ standing per day per activity program<br /><br>- Energy expenditure per day per activity program</p><br>