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Clinical Trials/NCT06586502
NCT06586502
Active, not recruiting
Not Applicable

Responding to Late Effects in Survivors of Childhood Cancer (RECOVER)

Remziye Semerci1 site in 1 country150 target enrollmentJune 1, 2024

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Survivorship
Sponsor
Remziye Semerci
Enrollment
150
Locations
1
Primary Endpoint
Caregiver Quality of Life Cancer
Status
Active, not recruiting
Last Updated
last year

Overview

Brief Summary

Survivors of childhood cancer need ongoing support to navigate their needs after cancer treatment. Using technology may offer us new ways to collect and share information about cancer survivorship follow-up with young survivors, their carers, and primary care providers.

Through the support of the Kids Cancer Project, in Phase 1 of this study, will co-design an electronic survivorship 'portal' that links young survivors with their cancer treatment information, and health care teams. In later Phases we will implement and evaluate the survivorship portal.

Detailed Description

The RECOVER study aims to develop and implement a comprehensive Model of Care for childhood cancer survivors, integrating technology and a human-centered co-design approach to provide continuous, holistic care. Our primary objectives are to assess the feasibility and acceptability of the RECOVER Model of Care in routine pediatric oncology practice. Secondary objectives include evaluating preliminary efficacy results and identifying factors that influence the successful adoption and integration of the model. Data Sources: This project will be conducted in three settings in Australia. The study will use a mixed methods approach, starting with a feasibility study (Phase 1), following implementation science methods to assess the integration of the new Model of Care (Phase 2), and culminating in a Type 2 Hybrid Implementation/Effectiveness non-randomized controlled trial (Phase 3) to compare historical and prospective data. The quantitative component of RECOVER (non-randomized controlled study) will involve the use of digital technologies to (1) enable multimodal, real-world data collection, (2) provide patients and caregivers with an interactive, supportive digital interface, and (3) equip healthcare professionals with a comprehensive patient-monitoring system. The qualitative component will determine end-user feasibility and acceptability through focus group workshops, surveys, and interviews.

Registry
clinicaltrials.gov
Start Date
June 1, 2024
End Date
December 2026
Last Updated
last year
Study Type
Interventional
Study Design
Sequential
Sex
All

Investigators

Sponsor
Remziye Semerci
Responsible Party
Sponsor Investigator
Principal Investigator

Remziye Semerci

Associate Professor

Trakya University

Eligibility Criteria

Inclusion Criteria

  • Patients aged 15-39 years who have completed cancer treatment.
  • Ability to read and understand English.
  • Willingness to comply with study procedures and provide informed consent.
  • Clinicians (doctors, nurses, allied health professionals) providing care through \*Queensland Health public hospitals

Exclusion Criteria

  • Patients deemed unsuitable by their clinical treatment team due to potential distress or lack of cognitive or communicative capacity.
  • None specified, as long as they meet the inclusion criteria.

Outcomes

Primary Outcomes

Caregiver Quality of Life Cancer

Time Frame: Baseline, Sixth and twelfth month

The scale is a validated and reliable measure, comprising 35 items on a 5-point Likert scale, which we have widely used in other studies with this population (Weitzner et al., 1999). We will compare outcomes of a historical control group (N=100), matched for child age and diagnosis, as closely as possible to identify any significant differences between groups that may be attributed to the RECOVER Model of care.

Pediatric Integrated Care Survey

Time Frame: Baseline, Sixth and twelfth month

Pediatric Integrated Care Survey

Distress Thermometer for Parents

Time Frame: Baseline, Sixth and twelfth month

The DT-P is a valid and reliable short screening tool for identifying parental distress. It was developed to determine parents' distress who had chronically ill children (0-18 years). The DT-P consists of a thermometer score from 0 (no distress) to 10 (extreme distress) and a problem list (practical, social, emotional, physical, cognitive, and parenting domains) (Haverman et al., 2013).

Study Sites (1)

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