Association Between Brain Blood Flow Regulation, Cognition, and Balance in Sports-Related Concussion
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 入组人数
- 79
- 试验地点
- 1
- 主要终点
- Cerebral blood flow regulation
研究概览
简要总结
The purpose of this study is to understand how biochemical markers in blood, balance disturbances, and cognitive performance are related to brain blood flow changes after a concussion.
详细描述
Comparisons will be made between control data and data following a concussion collected from athletes participating in contact-collision sports. For those suffering a concussion, comparisons will be made between day 3 (acute phase), day 21 (recovery phase), and 3 months post-concussion.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 30 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Student athletes actively participating in collegiate sports. Subjects should be wiling to provide informed consent for participation in the study.
排除标准
- •Participants who are unable to play as a result of injury. Presence of irregular heart beat.
结局指标
主要结局
Cerebral blood flow regulation
时间窗: Change in Control, 3 days post concussion, 21 days post concussion, and 3 months post concussion
Subject's cerebral blood flow regulation (cm/sec) at rest, during a cognitive test, and during a breathing test will be measured.
次要结局
- Balance Test(Control, 3 days post concussion, 21 days post concussion, 3 months post concussion)
- Blood Biomarkers(Control, 3 days post concussion, 21 days post concussion, 3 months post concussion)
- Cerebral Vasoreactivity(Control, 3 days post concussion, 21 days post concussion, 3 months post concussion)
- Orthostatic Tolerance Test(Control, 3 days post concussion, 21 days post concussion, 3 months post concussion)
- Memory Function Test(Control, 3 days post concussion, 21 days post concussion, 3 months post concussion)
研究者
Heather McClary
Director of Research Compliance
Southern Methodist University